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Efcab6 Efcab6 Park7 Park7 Efhc2 Efhc2 Tekt4 Tekt4 Tekt3 Tekt3 Ribc2 Ribc2 Tekt2 Tekt2 1700007K13Rik 1700007K13Rik Ccpg1os Ccpg1os Dnaic1 Dnaic1 Tekt1 Tekt1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Efcab6EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex. (1516 aa)    
Predicted Functional Partners:
Park7
Protein/nucleic acid deglycase DJ-1; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminoca [...]
   
 
 0.843
Efhc2
EF-hand domain-containing family member C2.
   
 
 0.757
Tekt4
Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility.
   
 
 0.736
Tekt3
Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility; Belongs to the tektin family.
   
 
 0.717
Ribc2
RIB43A-like with coiled-coils protein 2; Belongs to the RIB43A family.
   
 
 0.713
Tekt2
Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Belongs to the tektin family.
   
 
 0.712
1700007K13Rik
UPF0691 protein C9orf116 homolog.
   
 
 0.707
Ccpg1os
Cell cycle progression 1, opposite strand.
   
 
 0.706
Dnaic1
Dynein intermediate chain 1, axonemal; Part of the dynein complex of respiratory cilia.
   
 
 0.702
Tekt1
Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity).
   
 
 0.701
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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