Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Capza3 | Rnf141 | ENSMUSP00000038562 | ENSMUSP00000134781 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid. | RING finger protein 141; May be involved in spermatogenesis. | 0.448 |
| Ccdc42 | Kcnu1 | ENSMUSP00000114381 | ENSMUSP00000096457 | Coiled-coil domain-containing protein 42; Required for sperm development. Belongs to the CFAP73 family. | Potassium channel subfamily U member 1; Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina. Belongs to the potassium channel family. Calcium-activ [...] | 0.447 |
| Ccdc42 | Rnf141 | ENSMUSP00000114381 | ENSMUSP00000134781 | Coiled-coil domain-containing protein 42; Required for sperm development. Belongs to the CFAP73 family. | RING finger protein 141; May be involved in spermatogenesis. | 0.463 |
| Cux2 | Rnf141 | ENSMUSP00000107381 | ENSMUSP00000134781 | Homeobox protein cut-like 2; Transcription factor involved in the control of neuronal proliferation and differentiation in the brain. Regulates dendrite development and branching, dendritic spine formation, and synaptogenesis in cortical layers II-III. Binds to DNA in a sequence-specific manner. Belongs to the CUT homeobox family. | RING finger protein 141; May be involved in spermatogenesis. | 0.575 |
| Cux2 | Sall1 | ENSMUSP00000107381 | ENSMUSP00000034090 | Homeobox protein cut-like 2; Transcription factor involved in the control of neuronal proliferation and differentiation in the brain. Regulates dendrite development and branching, dendritic spine formation, and synaptogenesis in cortical layers II-III. Binds to DNA in a sequence-specific manner. Belongs to the CUT homeobox family. | Sal-like protein 1; Transcriptional repressor involved in organogenesis. Essential for ureteric bud invasion in kidney development. Homozygous deletion of SALL1 results in an incomplete ureteric bud outgrowth, a failure of tubule formation in the mesenchyme and an apoptosis of the mesenchyme; Belongs to the sal C2H2-type zinc-finger protein family. | 0.594 |
| Cux2 | Trim24 | ENSMUSP00000107381 | ENSMUSP00000031859 | Homeobox protein cut-like 2; Transcription factor involved in the control of neuronal proliferation and differentiation in the brain. Regulates dendrite development and branching, dendritic spine formation, and synaptogenesis in cortical layers II-III. Binds to DNA in a sequence-specific manner. Belongs to the CUT homeobox family. | Transcription intermediary factor 1-alpha; Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac) (By similarity). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis via its effects on p53/TP53 [...] | 0.705 |
| Golga3 | Rnf141 | ENSMUSP00000031477 | ENSMUSP00000134781 | Golgin subfamily A member 3; Plays an important role in spermatogenesis and/or testis development. Probably identical with the serologically detectable male antigen (SDM). Probably involved in maintaining Golgi structure. | RING finger protein 141; May be involved in spermatogenesis. | 0.465 |
| Kcnu1 | Ccdc42 | ENSMUSP00000096457 | ENSMUSP00000114381 | Potassium channel subfamily U member 1; Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina. Belongs to the potassium channel family. Calcium-activ [...] | Coiled-coil domain-containing protein 42; Required for sperm development. Belongs to the CFAP73 family. | 0.447 |
| Kcnu1 | Rnf141 | ENSMUSP00000096457 | ENSMUSP00000134781 | Potassium channel subfamily U member 1; Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina. Belongs to the potassium channel family. Calcium-activ [...] | RING finger protein 141; May be involved in spermatogenesis. | 0.449 |
| Ostf1 | Rnf141 | ENSMUSP00000025631 | ENSMUSP00000134781 | Osteoclast-stimulating factor 1; Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. | RING finger protein 141; May be involved in spermatogenesis. | 0.434 |
| Rassf3 | Rnf141 | ENSMUSP00000026902 | ENSMUSP00000134781 | Ras association domain-containing protein 3. | RING finger protein 141; May be involved in spermatogenesis. | 0.435 |
| Rnf141 | Capza3 | ENSMUSP00000134781 | ENSMUSP00000038562 | RING finger protein 141; May be involved in spermatogenesis. | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid. | 0.448 |
| Rnf141 | Ccdc42 | ENSMUSP00000134781 | ENSMUSP00000114381 | RING finger protein 141; May be involved in spermatogenesis. | Coiled-coil domain-containing protein 42; Required for sperm development. Belongs to the CFAP73 family. | 0.463 |
| Rnf141 | Cux2 | ENSMUSP00000134781 | ENSMUSP00000107381 | RING finger protein 141; May be involved in spermatogenesis. | Homeobox protein cut-like 2; Transcription factor involved in the control of neuronal proliferation and differentiation in the brain. Regulates dendrite development and branching, dendritic spine formation, and synaptogenesis in cortical layers II-III. Binds to DNA in a sequence-specific manner. Belongs to the CUT homeobox family. | 0.575 |
| Rnf141 | Golga3 | ENSMUSP00000134781 | ENSMUSP00000031477 | RING finger protein 141; May be involved in spermatogenesis. | Golgin subfamily A member 3; Plays an important role in spermatogenesis and/or testis development. Probably identical with the serologically detectable male antigen (SDM). Probably involved in maintaining Golgi structure. | 0.465 |
| Rnf141 | Kcnu1 | ENSMUSP00000134781 | ENSMUSP00000096457 | RING finger protein 141; May be involved in spermatogenesis. | Potassium channel subfamily U member 1; Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina. Belongs to the potassium channel family. Calcium-activ [...] | 0.449 |
| Rnf141 | Ostf1 | ENSMUSP00000134781 | ENSMUSP00000025631 | RING finger protein 141; May be involved in spermatogenesis. | Osteoclast-stimulating factor 1; Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. | 0.434 |
| Rnf141 | Rassf3 | ENSMUSP00000134781 | ENSMUSP00000026902 | RING finger protein 141; May be involved in spermatogenesis. | Ras association domain-containing protein 3. | 0.435 |
| Rnf141 | Rnf208 | ENSMUSP00000134781 | ENSMUSP00000109995 | RING finger protein 141; May be involved in spermatogenesis. | RING finger protein 208. | 0.496 |
| Rnf141 | Sall1 | ENSMUSP00000134781 | ENSMUSP00000034090 | RING finger protein 141; May be involved in spermatogenesis. | Sal-like protein 1; Transcriptional repressor involved in organogenesis. Essential for ureteric bud invasion in kidney development. Homozygous deletion of SALL1 results in an incomplete ureteric bud outgrowth, a failure of tubule formation in the mesenchyme and an apoptosis of the mesenchyme; Belongs to the sal C2H2-type zinc-finger protein family. | 0.581 |
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