node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
1700024P04Rik | H2al1a | ENSMUSP00000053046 | ENSMUSP00000140925 | Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm. | H2A histone family member L1A. | 0.615 |
1700024P04Rik | H2al3 | ENSMUSP00000053046 | ENSMUSP00000052025 | Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm. | H2A histone family member L3. | 0.631 |
1700024P04Rik | H2ap | ENSMUSP00000053046 | ENSMUSP00000043734 | Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm. | Huntingtin-interacting protein M. | 0.590 |
1700024P04Rik | H2bc1 | ENSMUSP00000053046 | ENSMUSP00000056604 | Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm. | Histone H2B type 1-A; Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells. Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones. In condensing spermatids, the heterodimer between H2AB1 and H2BC1/TH2B is loaded onto the nucleosomes and promotes loading of transition proteins (TNP1 and TNP2) onto the nucleosomes. Inclusion of the H2AB1-H2BC1/TH2B [...] | 0.442 |
1700024P04Rik | H3c6 | ENSMUSP00000053046 | ENSMUSP00000100739 | Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm. | H3 clustered histone 6. | 0.464 |
1700024P04Rik | Hils1 | ENSMUSP00000053046 | ENSMUSP00000039866 | Histone H2B subacrosomal variant; May act as an acrosome-nuclear docking protein in sperm. | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | 0.574 |
Btbd35f27 | H1f7 | ENSMUSP00000137066 | ENSMUSP00000127616 | BTB domain-containing 35, family member 27. | Testis-specific H1 histone; Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. | 0.432 |
Btbd35f27 | H2al1a | ENSMUSP00000137066 | ENSMUSP00000140925 | BTB domain-containing 35, family member 27. | H2A histone family member L1A. | 0.590 |
Gm6812 | H2al1a | ENSMUSP00000074433 | ENSMUSP00000140925 | Predicted gene 6812. | H2A histone family member L1A. | 0.629 |
Gm6812 | H2al3 | ENSMUSP00000074433 | ENSMUSP00000052025 | Predicted gene 6812. | H2A histone family member L3. | 0.691 |
Gm6812 | H2ap | ENSMUSP00000074433 | ENSMUSP00000043734 | Predicted gene 6812. | Huntingtin-interacting protein M. | 0.604 |
H1f6 | H1f7 | ENSMUSP00000037304 | ENSMUSP00000127616 | Histone H1t; Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination. Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration. | Testis-specific H1 histone; Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. | 0.846 |
H1f6 | H2al1a | ENSMUSP00000037304 | ENSMUSP00000140925 | Histone H1t; Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination. Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration. | H2A histone family member L1A. | 0.626 |
H1f6 | H2al3 | ENSMUSP00000037304 | ENSMUSP00000052025 | Histone H1t; Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination. Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration. | H2A histone family member L3. | 0.463 |
H1f6 | H2ap | ENSMUSP00000037304 | ENSMUSP00000043734 | Histone H1t; Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination. Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration. | Huntingtin-interacting protein M. | 0.425 |
H1f6 | H2bc1 | ENSMUSP00000037304 | ENSMUSP00000056604 | Histone H1t; Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination. Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration. | Histone H2B type 1-A; Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells. Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones. In condensing spermatids, the heterodimer between H2AB1 and H2BC1/TH2B is loaded onto the nucleosomes and promotes loading of transition proteins (TNP1 and TNP2) onto the nucleosomes. Inclusion of the H2AB1-H2BC1/TH2B [...] | 0.609 |
H1f6 | H3c6 | ENSMUSP00000037304 | ENSMUSP00000100739 | Histone H1t; Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination. Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration. | H3 clustered histone 6. | 0.449 |
H1f7 | Btbd35f27 | ENSMUSP00000127616 | ENSMUSP00000137066 | Testis-specific H1 histone; Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. | BTB domain-containing 35, family member 27. | 0.432 |
H1f7 | H1f6 | ENSMUSP00000127616 | ENSMUSP00000037304 | Testis-specific H1 histone; Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. | Histone H1t; Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination. Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration. | 0.846 |
H1f7 | H2al1a | ENSMUSP00000127616 | ENSMUSP00000140925 | Testis-specific H1 histone; Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. | H2A histone family member L1A. | 0.719 |