STRINGSTRING
Rnf39 Rnf39 Tcf19 Tcf19 Znrd1 Znrd1 Mog Mog Erich1 Erich1 Abcf1 Abcf1 Cfap161 Cfap161 Eps8l1 Eps8l1 Brsk1 Brsk1 Tjap1 Tjap1 Lcn8 Lcn8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rnf39RING finger protein 39; May play a role in prolonged long term-potentiation (LTP) maintenance. (352 aa)    
Predicted Functional Partners:
Tcf19
Transcription factor 19.
      
 0.745
Znrd1
DNA-directed RNA polymerase I subunit RPA12; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
   
 
 0.694
Mog
Myelin-oligodendrocyte glycoprotein; Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.
  
   
 0.615
Erich1
Glutamate-rich 1.
      
 0.590
Abcf1
ATP-binding cassette sub-family F member 1; Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis (By similarity).
    
 
 0.567
Cfap161
Similar to RIKEN cDNA 1700026D08, isoform CRA_a.
    
 
 0.529
Eps8l1
EPS8-like 1 (Predicted).
  
  
 0.516
Brsk1
Serine/threonine-protein kinase BRSK1; Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Thr-523' and 'Ser-573'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in postmitotic neurons, leading to down-regulate WEE1 [...]
      
 0.497
Tjap1
Tight junction-associated protein 1.
      
 0.495
Lcn8
Lipocalin 8 (Predicted); Belongs to the calycin superfamily. Lipocalin family.
      
 0.489
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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