Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Mvb12a | Mvb12b | ENSRNOP00000024413 | ENSRNOP00000023172 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Multivesicular body subunit 12B. | 0.919 |
| Mvb12a | Pdcd6ip | ENSRNOP00000024413 | ENSRNOP00000012114 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Programmed cell death 6-interacting protein; Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction integrity. Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway requires [...] | 0.940 |
| Mvb12a | Tsg101 | ENSRNOP00000024413 | ENSRNOP00000018194 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). It may also play a role in the [...] | 0.987 |
| Mvb12a | Ubap1 | ENSRNOP00000024413 | ENSRNOP00000062034 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Ubiquitin-associated protein 1; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2. | 0.927 |
| Mvb12a | Vps28 | ENSRNOP00000024413 | ENSRNOP00000019707 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Vacuolar protein sorting-associated protein 28 homolog; Component of the endosomal sorting complex required for transport-I (ESCRT-I) complex, a regulator of vesicular trafficking process. The ESCRT-I complex participates in the sorting of membrane proteins into vesicles that bud into late endosomal compartments called multivesicular bodies, and is also involved in the budding of many viruses. | 0.995 |
| Mvb12a | Vps37a | ENSRNOP00000024413 | ENSRNOP00000016321 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Similar to DNA segment, Chr 8, ERATO Doi 531, expressed, isoform CRA_c. | 0.967 |
| Mvb12a | Vps37b | ENSRNOP00000024413 | ENSRNOP00000001445 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Vacuolar protein sorting 37B (Yeast) (Predicted), isoform CRA_b. | 0.986 |
| Mvb12a | Vps37c | ENSRNOP00000024413 | ENSRNOP00000070431 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Vacuolar protein sorting 37C (Yeast) (Predicted). | 0.966 |
| Mvb12a | Vps37c-2 | ENSRNOP00000024413 | ENSRNOP00000074984 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | VPS37C subunit of ESCRT-I. | 0.966 |
| Mvb12a | Vps37d | ENSRNOP00000024413 | ENSRNOP00000067165 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | VPS37D subunit of ESCRT-I. | 0.957 |
| Mvb12b | Mvb12a | ENSRNOP00000023172 | ENSRNOP00000024413 | Multivesicular body subunit 12B. | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | 0.919 |
| Mvb12b | Pdcd6ip | ENSRNOP00000023172 | ENSRNOP00000012114 | Multivesicular body subunit 12B. | Programmed cell death 6-interacting protein; Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction integrity. Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway requires [...] | 0.933 |
| Mvb12b | Tsg101 | ENSRNOP00000023172 | ENSRNOP00000018194 | Multivesicular body subunit 12B. | Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). It may also play a role in the [...] | 0.985 |
| Mvb12b | Ubap1 | ENSRNOP00000023172 | ENSRNOP00000062034 | Multivesicular body subunit 12B. | Ubiquitin-associated protein 1; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2. | 0.907 |
| Mvb12b | Vps28 | ENSRNOP00000023172 | ENSRNOP00000019707 | Multivesicular body subunit 12B. | Vacuolar protein sorting-associated protein 28 homolog; Component of the endosomal sorting complex required for transport-I (ESCRT-I) complex, a regulator of vesicular trafficking process. The ESCRT-I complex participates in the sorting of membrane proteins into vesicles that bud into late endosomal compartments called multivesicular bodies, and is also involved in the budding of many viruses. | 0.991 |
| Mvb12b | Vps37a | ENSRNOP00000023172 | ENSRNOP00000016321 | Multivesicular body subunit 12B. | Similar to DNA segment, Chr 8, ERATO Doi 531, expressed, isoform CRA_c. | 0.968 |
| Mvb12b | Vps37b | ENSRNOP00000023172 | ENSRNOP00000001445 | Multivesicular body subunit 12B. | Vacuolar protein sorting 37B (Yeast) (Predicted), isoform CRA_b. | 0.988 |
| Mvb12b | Vps37c | ENSRNOP00000023172 | ENSRNOP00000070431 | Multivesicular body subunit 12B. | Vacuolar protein sorting 37C (Yeast) (Predicted). | 0.967 |
| Mvb12b | Vps37c-2 | ENSRNOP00000023172 | ENSRNOP00000074984 | Multivesicular body subunit 12B. | VPS37C subunit of ESCRT-I. | 0.967 |
| Mvb12b | Vps37d | ENSRNOP00000023172 | ENSRNOP00000067165 | Multivesicular body subunit 12B. | VPS37D subunit of ESCRT-I. | 0.963 |
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