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Gtpbp3 Gtpbp3 Mto1 Mto1 Trmu Trmu Ergic1 Ergic1 Ergic3 Ergic3 Ergic2 Ergic2 mrpl11 mrpl11 Gtpbp8 Gtpbp8 Mrm3 Mrm3 Mrpl21 Mrpl21 Mtg1 Mtg1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gtpbp3tRNA modification GTPase GTPBP3, mitochondrial; GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (492 aa)    
Predicted Functional Partners:
Mto1
Mitochondrial tRNA translation optimization 1.
 
 0.990
Trmu
Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. Belongs to the MnmA/TRMU family.
  
 0.946
Ergic1
Endoplasmic reticulum-golgi intermediate compartment 1.
  
 0.929
Ergic3
ERGIC and golgi 3 (Predicted).
  
 0.929
Ergic2
RCG29652, isoform CRA_c.
  
 0.929
mrpl11
39S ribosomal protein L11, mitochondrial; Belongs to the universal ribosomal protein uL11 family.
   
 
 0.921
Gtpbp8
GTP-binding protein 8.
    
 
 0.893
Mrm3
Similar to putative RNA methyltransferase (Predicted).
  
 
 0.839
Mrpl21
Mitochondrial ribosomal protein L21 (Predicted), isoform CRA_a.
   
 
 0.838
Mtg1
Mitochondrial GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
 
 0.837
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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