node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GGCX | NQO1 | ENSCPOP00000001387 | ENSCPOP00000011185 | Gamma-glutamyl carboxylase. | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. | 0.941 |
GGCX | VKORC1 | ENSCPOP00000001387 | ENSCPOP00000005687 | Gamma-glutamyl carboxylase. | Vitamin K epoxide reductase complex subunit 1. | 0.962 |
GGCX | Vkorc1l1 | ENSCPOP00000001387 | ENSCPOP00000029591 | Gamma-glutamyl carboxylase. | VKc domain-containing protein. | 0.886 |
HMOX1 | KEAP1 | ENSCPOP00000019892 | ENSCPOP00000033001 | Heme oxygenase 1. | Kelch like ECH associated protein 1. | 0.772 |
HMOX1 | NFE2L2 | ENSCPOP00000019892 | ENSCPOP00000028187 | Heme oxygenase 1. | Nuclear factor, erythroid 2 like 2. | 0.794 |
HMOX1 | NQO1 | ENSCPOP00000019892 | ENSCPOP00000011185 | Heme oxygenase 1. | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. | 0.738 |
KEAP1 | HMOX1 | ENSCPOP00000033001 | ENSCPOP00000019892 | Kelch like ECH associated protein 1. | Heme oxygenase 1. | 0.772 |
KEAP1 | NFE2L2 | ENSCPOP00000033001 | ENSCPOP00000028187 | Kelch like ECH associated protein 1. | Nuclear factor, erythroid 2 like 2. | 0.999 |
KEAP1 | NQO1 | ENSCPOP00000033001 | ENSCPOP00000011185 | Kelch like ECH associated protein 1. | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. | 0.781 |
KEAP1 | TP53 | ENSCPOP00000033001 | ENSCPOP00000029751 | Kelch like ECH associated protein 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.456 |
NFE2L2 | HMOX1 | ENSCPOP00000028187 | ENSCPOP00000019892 | Nuclear factor, erythroid 2 like 2. | Heme oxygenase 1. | 0.794 |
NFE2L2 | KEAP1 | ENSCPOP00000028187 | ENSCPOP00000033001 | Nuclear factor, erythroid 2 like 2. | Kelch like ECH associated protein 1. | 0.999 |
NFE2L2 | NQO1 | ENSCPOP00000028187 | ENSCPOP00000011185 | Nuclear factor, erythroid 2 like 2. | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. | 0.770 |
NFE2L2 | TP53 | ENSCPOP00000028187 | ENSCPOP00000029751 | Nuclear factor, erythroid 2 like 2. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.469 |
NQO1 | GGCX | ENSCPOP00000011185 | ENSCPOP00000001387 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. | Gamma-glutamyl carboxylase. | 0.941 |
NQO1 | HMOX1 | ENSCPOP00000011185 | ENSCPOP00000019892 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. | Heme oxygenase 1. | 0.738 |
NQO1 | KEAP1 | ENSCPOP00000011185 | ENSCPOP00000033001 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. | Kelch like ECH associated protein 1. | 0.781 |
NQO1 | NFE2L2 | ENSCPOP00000011185 | ENSCPOP00000028187 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. | Nuclear factor, erythroid 2 like 2. | 0.770 |
NQO1 | ODC1 | ENSCPOP00000011185 | ENSCPOP00000007619 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. | Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.767 |
NQO1 | RIDA | ENSCPOP00000011185 | ENSCPOP00000028780 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. | Reactive intermediate imine deaminase A homolog. | 0.741 |