STRINGSTRING
rlmH rlmH rsfS rsfS rsmI rsmI DSY5017 DSY5017 DSY4114 DSY4114 DSY5016 DSY5016 DSY2672 DSY2672 rsmH rsmH ribD ribD DSY1307 DSY1307 nadD nadD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmHHypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (160 aa)    
Predicted Functional Partners:
rsfS
Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
  
 0.831
rsmI
Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
   
 0.709
DSY5017
Hypothetical protein; Similarity to COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I(Evalue: 5E-47).
 
     0.685
DSY4114
Hypothetical protein; Similarity to COG0642 Signal transduction histidine kinase(Evalue: 4E-36).
  
    0.600
DSY5016
Hypothetical protein; Similarity to COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain(Evalue: 3E-61).
       0.575
DSY2672
Hypothetical protein; Similarity to COG0742 N6-adenine-specific methylase(Evalue: 1E-33).
 
   
 0.566
rsmH
Hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
   
 0.564
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.558
DSY1307
Hypothetical protein; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
  
   
 0.543
nadD
Nicotinate nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.517
Your Current Organism:
Desulfitobacterium hafniense
NCBI taxonomy Id: 138119
Other names: D. hafniense Y51, Desulfitobacterium hafniense Y51, Desulfitobacterium hafniense str. Y51, Desulfitobacterium hafniense strain Y51, Desulfitobacterium sp. Y51
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