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purA purA purB purB purH purH pyrB pyrB argG argG nadB nadB aspC aspC guaB guaB surE surE aspA aspA ansA ansA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (436 aa)    
Predicted Functional Partners:
purB
Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.995
purH
AICARFT/IMPCHase bienzyme:Methylglyoxal synthase-like domain; COG138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Nucleotide transport and metabolism].
  
 0.975
pyrB
COG540 Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.940
argG
COG137 Argininosuccinate synthase [Amino acid transport and metabolism]; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 
 0.930
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.913
aspC
Aminotransferases class-I; COG436 Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism].
   
 0.912
guaB
COG516 IMP dehydrogenase/GMP reductase [Nucleotide transport and metabolism].
   
 
  0.912
surE
Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.910
aspA
Putative aspartoacylase; COG2988 Succinylglutamate desuccinylase [Amino acid transport and metabolism]; Belongs to the AspA/AstE family. Aspartoacylase subfamily.
     
  0.900
ansA
COG4448 L-asparaginase II [Amino acid transport and metabolism].
     
  0.900
Your Current Organism:
Prochlorococcus marinus MIT9515
NCBI taxonomy Id: 167542
Other names: P. marinus str. MIT 9515, Prochlorococcus marinus str. MIT 9515
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