STRINGSTRING
dapAL dapAL PAE2876 PAE2876 PAE2868 PAE2868 rps17e rps17e PAE2877 PAE2877 taw3 taw3 rps15 rps15 PAE3044 PAE3044 PAE3437 PAE3437 fusA fusA rps3 rps3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
dapALDihydrodipicolinate synthase; Amino acid biosynthesis; Aspartate family; Belongs to the DapA family. (301 aa)    
Predicted Functional Partners:
PAE2876
Aspartate-semialdehyde dehydrogenase (asd); Amino acid biosynthesis; Aspartate family.
 
 
 0.985
PAE2868
Homoserine dehydrogenase; Amino acid biosynthesis; Aspartate family.
  
 
 0.952
rps17e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eS17 family.
  
    0.879
PAE2877
Aspartate kinase; Amino acid biosynthesis; Aspartate family.
 
  
 0.797
taw3
Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family.
 
     0.786
rps15
Protein synthesis; Ribosomal proteins: synthesis and modification.
  
    0.784
PAE3044
Conserved hypothetical protein; Belongs to the PDCD5 family.
 
    0.762
PAE3437
Glucokinase (ROK family protein), conjectural; Energy metabolism; Sugars.
 
  
 0.749
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
  
  
 0.742
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
  
 0.737
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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