STRINGSTRING
pelA pelA rnp2 rnp2 PF0670 PF0670 tuf tuf rpl15e rpl15e rps6e rps6e rps3ae rps3ae rps17e rps17e rpl19e rpl19e rpl37ae rpl37ae argS argS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pelACell division protein pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (356 aa)    
Predicted Functional Partners:
rnp2
Hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. The RNA is catalytic, but its KM for pre-tRNA is 170-fold decreased in the presence of the 4 known protein subunits (Rnp1-4). The protein subunits also decrease the amount of Mg(2+) needed for activity.
 
     0.855
PF0670
RNase l inhibitor; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS.
 
 
 0.844
tuf
Translation elongation factor eF-1, subunit alpha (tuf); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
   
 
 0.838
rpl15e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl15E).
 
 
   0.834
rps6e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps6E).
 
 
 
 0.828
rps3ae
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps3AE).
  
 
   0.810
rps17e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps17E).
 
 
 
 0.786
rpl19e
LSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
 
 
 
 0.778
rpl37ae
LSU ribosomal protein L37AE; Binds to the 23S rRNA.
  
 
   0.778
argS
arginyl-tRNA synthetase; Function Code: 13.1 Translation: Amino acyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.774
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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