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PF1542 PF1542 rpl37e rpl37e fusA fusA hel308 hel308 eif5a eif5a PF1087 PF1087 flpA flpA rpoN rpoN rpoP rpoP rps24e rps24e rpoH rpoH
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PF1542Small nuclear ribonucleoprotein, putative; Function Code: 12.3 Transcription: RNA processing; Belongs to the snRNP Sm proteins family. (76 aa)    
Predicted Functional Partners:
rpl37e
LSU ribosomal protein L37E; Binds to the 23S rRNA.
  
  
 0.986
fusA
Elongation factor 2 (EF-2); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
   
 0.979
hel308
Helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. Unwinds the lagging strand from forked DNA structures in a 3'-5' direction. PCNA, the DNA polymerase sliding clamp subunit, stimulates the helicase activity, and may alter substrate specificity. Unwinds branched DNA (Holliday junctions) in an ATP-dependent fashion; ss- and dsDNA stimulate ATPase to the greatest extent, although it preferentially binds DNA with a single-stranded region. Processes a RecA-mediated recombination intermediate between gapped circular and homolog [...]
   
 0.933
eif5a
Translation initiation factor eIF-5a; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
    0.918
PF1087
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical; Belongs to the PDCD5 family.
   
    0.904
flpA
Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
   
 0.856
rpoN
DNA-directed RNA polymerase subunit n; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
 
  0.854
rpoP
Hypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
   
 0.829
rps24e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps24E).
   
 
 0.821
rpoH
DNA-directed RNA polymerase subunit h; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
 
  0.819
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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