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dnaE2 dnaE2 imuB imuB imuA imuA dinB dinB dnaN dnaN CC_1823 CC_1823 HolA HolA dnaX dnaX ssb ssb CC_1693 CC_1693 recA recA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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dnaE2DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). Along with ImuA and ImuB is required for the error-prone processing of DNA lesions (By similarity). (1083 aa)    
Predicted Functional Partners:
imuB
Hypothetical protein; Along with DnaE2 and ImuA is required for the error-prone processing of DNA lesions.
 
  
 0.986
imuA
Hypothetical protein; Along with DnaE2 and ImuB is required for the error-prone processing of DNA lesions.
 
  
 0.975
dinB
DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
  
 0.883
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.873
CC_1823
DNA polymerase III, delta prime subunit; Identified by match to protein family HMM.
  
 
 0.845
HolA
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.826
dnaX
DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 
 0.820
ssb
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.820
CC_1693
DNA polymerase III, chi subunit, putative; Similar to SP:P28905 SP:P11649 GB:L04574 GB:X15130 GB:Z14155; identified by sequence similarity; putative.
  
 
 0.801
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.800
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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