node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Noca_0260 | Noca_0261 | Noca_0260 | Noca_0261 | TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: rha:RHA1_ro02720 NAD(P) transhydrogenase alpha subunit. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
Noca_0260 | Noca_1514 | Noca_0260 | Noca_1514 | TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: rha:RHA1_ro02720 NAD(P) transhydrogenase alpha subunit. | PFAM: NUDIX hydrolase; KEGG: tfu:Tfu_0527 conserved hypothetical protein. | 0.900 |
Noca_0260 | cobB | Noca_0260 | Noca_0265 | TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: rha:RHA1_ro02720 NAD(P) transhydrogenase alpha subunit. | PFAM: Silent information regulator protein Sir2; KEGG: sal:Sala_2748 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | 0.910 |
Noca_0260 | nadD | Noca_0260 | Noca_1820 | TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: rha:RHA1_ro02720 NAD(P) transhydrogenase alpha subunit. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.908 |
Noca_0260 | nadE | Noca_0260 | Noca_2044 | TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: rha:RHA1_ro02720 NAD(P) transhydrogenase alpha subunit. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.912 |
Noca_0260 | nadK | Noca_0260 | Noca_2481 | TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: rha:RHA1_ro02720 NAD(P) transhydrogenase alpha subunit. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.916 |
Noca_0261 | Noca_0260 | Noca_0261 | Noca_0260 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: rha:RHA1_ro02720 NAD(P) transhydrogenase alpha subunit. | 0.999 |
Noca_0261 | Noca_1514 | Noca_0261 | Noca_1514 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | PFAM: NUDIX hydrolase; KEGG: tfu:Tfu_0527 conserved hypothetical protein. | 0.900 |
Noca_0261 | cobB | Noca_0261 | Noca_0265 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | PFAM: Silent information regulator protein Sir2; KEGG: sal:Sala_2748 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | 0.903 |
Noca_0261 | nadD | Noca_0261 | Noca_1820 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.905 |
Noca_0261 | nadE | Noca_0261 | Noca_2044 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.920 |
Noca_0261 | nadK | Noca_0261 | Noca_2481 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.906 |
Noca_0463 | Noca_1307 | Noca_0463 | Noca_1307 | KEGG: fra:Francci3_4378 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.976 |
Noca_0463 | Noca_1514 | Noca_0463 | Noca_1514 | KEGG: fra:Francci3_4378 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | PFAM: NUDIX hydrolase; KEGG: tfu:Tfu_0527 conserved hypothetical protein. | 0.906 |
Noca_0463 | Noca_2324 | Noca_0463 | Noca_2324 | KEGG: fra:Francci3_4378 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | PFAM: CinA domain protein; KEGG: fal:FRAAL5732 competence-inducible (CinA-like) protein; Belongs to the CinA family. | 0.915 |
Noca_0463 | nadD | Noca_0463 | Noca_1820 | KEGG: fra:Francci3_4378 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.965 |
Noca_0463 | nadE | Noca_0463 | Noca_2044 | KEGG: fra:Francci3_4378 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.671 |
Noca_1307 | Noca_0463 | Noca_1307 | Noca_0463 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | KEGG: fra:Francci3_4378 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 0.976 |
Noca_1307 | Noca_1514 | Noca_1307 | Noca_1514 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | PFAM: NUDIX hydrolase; KEGG: tfu:Tfu_0527 conserved hypothetical protein. | 0.921 |
Noca_1307 | Noca_2324 | Noca_1307 | Noca_2324 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | PFAM: CinA domain protein; KEGG: fal:FRAAL5732 competence-inducible (CinA-like) protein; Belongs to the CinA family. | 0.938 |