node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OEOE_0002 | OEOE_0426 | OEOE_0002 | OEOE_0426 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase PcrA. | 0.854 |
OEOE_0002 | OEOE_0794 | OEOE_0002 | OEOE_0794 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Nucleotidyltransferase/DNA polymerase for DNA repair; Belongs to the DNA polymerase type-Y family. | 0.991 |
OEOE_0002 | OEOE_1233 | OEOE_0002 | OEOE_1233 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.452 |
OEOE_0002 | fumC | OEOE_0002 | OEOE_0029 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.406 |
OEOE_0002 | polA | OEOE_0002 | OEOE_0673 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
OEOE_0002 | recA | OEOE_0002 | OEOE_1382 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.824 |
OEOE_0002 | rpoB | OEOE_0002 | OEOE_1375 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.621 |
OEOE_0426 | OEOE_0002 | OEOE_0426 | OEOE_0002 | ATP-dependent DNA helicase PcrA. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.854 |
OEOE_0426 | OEOE_0794 | OEOE_0426 | OEOE_0794 | ATP-dependent DNA helicase PcrA. | Nucleotidyltransferase/DNA polymerase for DNA repair; Belongs to the DNA polymerase type-Y family. | 0.465 |
OEOE_0426 | OEOE_1233 | OEOE_0426 | OEOE_1233 | ATP-dependent DNA helicase PcrA. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.479 |
OEOE_0426 | lexA | OEOE_0426 | OEOE_0970 | ATP-dependent DNA helicase PcrA. | Transcriptional regulator, xre family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.462 |
OEOE_0426 | polA | OEOE_0426 | OEOE_0673 | ATP-dependent DNA helicase PcrA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.808 |
OEOE_0426 | recA | OEOE_0426 | OEOE_1382 | ATP-dependent DNA helicase PcrA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.815 |
OEOE_0426 | recX | OEOE_0426 | OEOE_1698 | ATP-dependent DNA helicase PcrA. | Hypothetical protein, RecX family; Modulates RecA activity; Belongs to the RecX family. | 0.425 |
OEOE_0426 | rpoB | OEOE_0426 | OEOE_1375 | ATP-dependent DNA helicase PcrA. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.695 |
OEOE_0794 | OEOE_0002 | OEOE_0794 | OEOE_0002 | Nucleotidyltransferase/DNA polymerase for DNA repair; Belongs to the DNA polymerase type-Y family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.991 |
OEOE_0794 | OEOE_0426 | OEOE_0794 | OEOE_0426 | Nucleotidyltransferase/DNA polymerase for DNA repair; Belongs to the DNA polymerase type-Y family. | ATP-dependent DNA helicase PcrA. | 0.465 |
OEOE_0794 | OEOE_1233 | OEOE_0794 | OEOE_1233 | Nucleotidyltransferase/DNA polymerase for DNA repair; Belongs to the DNA polymerase type-Y family. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.554 |
OEOE_0794 | lexA | OEOE_0794 | OEOE_0970 | Nucleotidyltransferase/DNA polymerase for DNA repair; Belongs to the DNA polymerase type-Y family. | Transcriptional regulator, xre family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.868 |
OEOE_0794 | polA | OEOE_0794 | OEOE_0673 | Nucleotidyltransferase/DNA polymerase for DNA repair; Belongs to the DNA polymerase type-Y family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.753 |