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plsX plsX plsY plsY fabH fabH b4041 b4041 fabD fabD rpmF rpmF YPO1463 YPO1463 YPO1594 YPO1594 rplF rplF parF parF rplU rplU
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
plsXFatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (344 aa)    
Predicted Functional Partners:
plsY
Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
 
  
 0.995
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
  
 0.982
b4041
Similar to Escherichia coli glycerol-3-phosphate acyltransferase PlsB SW:PLSB_ECOLI (P00482) (806 aa) fasta scores: E(): 0, 80.2% id in 802 aa; Belongs to the GPAT/DAPAT family.
   
 
 0.973
fabD
Similar to Escherichia coli malonyl CoA-acyl carrier protein transacylase FabD or TfpA SW:FABD_ECOLI (P25715) (308 aa) fasta scores: E(): 0, 78.5% id in 307 aa, and to Salmonella typhimurium malonyl CoA-acyl carrier protein transacylase SW:FABD_SALTY (O85140) (308 aa) fasta scores: E(): 0, 79.7% id in 306 aa.
  
  
 0.965
rpmF
50S ribosomal protein L32; Similar to Escherichia coli, and Salmonella typhimurium 50S ribosomal protein L32 SW:RL32_ECOLI (P02435) (56 aa) fasta scores: E(): 3.4e-20, 90.7% id in 54 aa, and to Haemophilus influenzae 50S ribosomal protein L32 RpmF or Rpl32 or Hi0158 SW:RL32_HAEIN (P44368) (55 aa) fasta scores: E(): 4.3e-19, 83.0% id in 53 aa; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.964
YPO1463
Putative acyl transferase; Similar to Bacillus subtilis malonyl CoA-acyl carrier protein transacylase FabD SW:FABD_BACSU (P71019) (317 aa) fasta scores: E(): 4.5e-28, 36.2% id in 290 aa,and to Bacillus subtilis putative polyketide synthesis protein PksC TR:O34825 (EMBL:Z99112) (288 aa) fasta scores: E(): 0, 45.1% id in 275 aa.
  
  
 0.883
YPO1594
Similar to Escherichia coli hypothetical protein Yced or G30K SW:YCED_ECOLI (P14189) (173 aa) fasta scores: E(): 0, 79.7% id in 172 aa, and to Haemophilus influenzae hypothetical protein HI0159 SW:YCED_HAEIN (P43790) (174 aa) fasta scores: E(): 0, 55.5% id in 173 aa.
  
    0.879
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.871
parF
Putative acyltransferase; Similar to Escherichia coli 1-acyl-sn-glycerol-3-phosphate acyltransferase PlsC SW:PLSC_ECOLI (P26647) (245 aa) fasta scores: E(): 0, 71.7% id in 244 aa, and to Salmonella typhimurium 1-acyl-sn-glycerol-3-phosphate acyltransferase PlsC SW:PLSC_SALTY (P26974) (245 aa) fasta scores: E(): 0, 71.7% id in 244 aa.
  
 
 0.865
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
    0.857
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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