Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ams | cca | YPO1590 | YPO0650 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.666 |
| ams | rnpA | YPO1590 | YPO4101 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | Ribonuclease P protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.641 |
| ams | rnt | YPO1590 | YPO2382 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.660 |
| ams | rph | YPO1590 | YPO0044 | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.701 |
| cca | ams | YPO0650 | YPO1590 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.666 |
| cca | holA | YPO0650 | YPO2608 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Similar to Escherichia coli DNA polymerase III,delta subunit HolA SW:HOLA_ECOLI (P28630) (343 aa) fasta scores: E(): 0, 71.9% id in 342 aa, and to Vibrio cholerae DNA polymerase III, delta subunit VC0953 TR:Q9KTE9 (EMBL:AE004177) (342 aa) fasta scores: E(): 0, 48.5% id in 332 aa. | 0.558 |
| cca | rnpA | YPO0650 | YPO4101 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Ribonuclease P protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.653 |
| cca | rnt | YPO0650 | YPO2382 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.716 |
| dnaE | dnaN | YPO1059 | YPO4096 | Similar to Escherichia coli DNA polymerase III,alpha chain DnaE SW:DP3A_ECOLI (P10443) (1160 aa) fasta scores: E(): 0, 89.0% id in 1160 aa. | DNA polymerase III, beta subunit protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initi [...] | 0.997 |
| dnaE | dnaX | YPO1059 | YPO3122 | Similar to Escherichia coli DNA polymerase III,alpha chain DnaE SW:DP3A_ECOLI (P10443) (1160 aa) fasta scores: E(): 0, 89.0% id in 1160 aa. | DNA polymerase III subunit Tau (contains DNA polymerase III subunit Gamma); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.998 |
| dnaE | holA | YPO1059 | YPO2608 | Similar to Escherichia coli DNA polymerase III,alpha chain DnaE SW:DP3A_ECOLI (P10443) (1160 aa) fasta scores: E(): 0, 89.0% id in 1160 aa. | Similar to Escherichia coli DNA polymerase III,delta subunit HolA SW:HOLA_ECOLI (P28630) (343 aa) fasta scores: E(): 0, 71.9% id in 342 aa, and to Vibrio cholerae DNA polymerase III, delta subunit VC0953 TR:Q9KTE9 (EMBL:AE004177) (342 aa) fasta scores: E(): 0, 48.5% id in 332 aa. | 0.996 |
| dnaE | holE | YPO1059 | YPO1782 | Similar to Escherichia coli DNA polymerase III,alpha chain DnaE SW:DP3A_ECOLI (P10443) (1160 aa) fasta scores: E(): 0, 89.0% id in 1160 aa. | Similar to Escherichia coli DNA polymerase III,theta subunit HolE SW:HOLE_ECOLI (P28689) (76 aa) fasta scores: E(): 3.5e-16, 64.5% id in 76 aa. | 0.994 |
| dnaE | rnt | YPO1059 | YPO2382 | Similar to Escherichia coli DNA polymerase III,alpha chain DnaE SW:DP3A_ECOLI (P10443) (1160 aa) fasta scores: E(): 0, 89.0% id in 1160 aa. | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.888 |
| dnaN | dnaE | YPO4096 | YPO1059 | DNA polymerase III, beta subunit protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initi [...] | Similar to Escherichia coli DNA polymerase III,alpha chain DnaE SW:DP3A_ECOLI (P10443) (1160 aa) fasta scores: E(): 0, 89.0% id in 1160 aa. | 0.997 |
| dnaN | dnaX | YPO4096 | YPO3122 | DNA polymerase III, beta subunit protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initi [...] | DNA polymerase III subunit Tau (contains DNA polymerase III subunit Gamma); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.998 |
| dnaN | holA | YPO4096 | YPO2608 | DNA polymerase III, beta subunit protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initi [...] | Similar to Escherichia coli DNA polymerase III,delta subunit HolA SW:HOLA_ECOLI (P28630) (343 aa) fasta scores: E(): 0, 71.9% id in 342 aa, and to Vibrio cholerae DNA polymerase III, delta subunit VC0953 TR:Q9KTE9 (EMBL:AE004177) (342 aa) fasta scores: E(): 0, 48.5% id in 332 aa. | 0.998 |
| dnaN | holE | YPO4096 | YPO1782 | DNA polymerase III, beta subunit protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initi [...] | Similar to Escherichia coli DNA polymerase III,theta subunit HolE SW:HOLE_ECOLI (P28689) (76 aa) fasta scores: E(): 3.5e-16, 64.5% id in 76 aa. | 0.981 |
| dnaN | rnpA | YPO4096 | YPO4101 | DNA polymerase III, beta subunit protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initi [...] | Ribonuclease P protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.752 |
| dnaN | rnt | YPO4096 | YPO2382 | DNA polymerase III, beta subunit protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initi [...] | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.886 |
| dnaX | dnaE | YPO3122 | YPO1059 | DNA polymerase III subunit Tau (contains DNA polymerase III subunit Gamma); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Similar to Escherichia coli DNA polymerase III,alpha chain DnaE SW:DP3A_ECOLI (P10443) (1160 aa) fasta scores: E(): 0, 89.0% id in 1160 aa. | 0.998 |
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