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ccmA ccmA ccmB ccmB ccmC ccmC ccmE ccmE ccmD ccmD ccmF ccmF ccmH ccmH ccmG ccmG vacJ vacJ napC napC napB napB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
ccmAPutative heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (218 aa)    
Predicted Functional Partners:
ccmB
Heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 0.999
ccmC
Putative heme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.999
ccmE
Putative cytochrome c-type biogenesis protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.961
ccmD
Putative heme exporter protein D; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
 
 
 0.955
ccmF
Similar to Escherichia coli cytochrome c-type biogenesis protein CcmF SW:CCMF_ECOLI (P33927) (647 aa) fasta scores: E(): 0, 71.1% id in 654 aa, and to Pantoea citrea CcmF-like protein TR:Q9Z646 (EMBL:AF103874) (655 aa) fasta scores: E(): 0, 78.8% id in 646 aa.
 
  
 0.952
ccmH
Putative cytochrome c-type biogenesis protein; Possible subunit of a heme lyase.
 
   
 0.937
ccmG
Thiol:disulfide interchange protein DsbE; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity); Belongs to the thioredoxin family. DsbE subfamily.
 
   
 0.928
vacJ
Probable lipoprotein, similar to Shigella flexneri virulence protein required for intercellular spreading,VacJ SW:VACJ_SHIFL (P43262) (251 aa) fasta scores: E(): 0,75.0% id in 252 aa, and to Escherichia coli lipoprotein VacJ SW:VACJ_ECOLI (P76506) (251 aa) fasta scores: E(): 0,75.0% id in 252 aa.
       0.566
napC
Similar to Escherichia coli cytochrome C-type protein NapC SW:NAPC_ECOLI (P33932) (200 aa) fasta scores: E(): 0, 75.5% id in 200 aa, and to Haemophilus influenzae cytochrome C-type protein NapC or hi0348 SW:NAPC_HAEIN (P44655) (200 aa) fasta scores: E(): 0, 61.8% id in 199 aa.
 
  
 0.539
napB
Cytochrome C-type protein NapB precursor; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.
 
    0.427
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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