STRINGSTRING
YPO3287 YPO3287 YPO3943 YPO3943 proA proA barA barA arcB arcB yohK yohK YPO3965 YPO3965 YPO0256 YPO0256 rcsC rcsC tyrA tyrA YPO1181 YPO1181
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
YPO3287Similar to Vibrio cholerae response regulator VC0693 TR:Q9KU36 (EMBL:AE004155) (237 aa) fasta scores: E(): 0,56.4% id in 236 aa, and to Escherichia coli hypothetical protein YehT SW:YEHT_ECOLI (P33356) (244 aa) fasta scores: E(): 0, 57.7% id in 239 aa. (238 aa)    
Predicted Functional Partners:
YPO3943
Putative membrane protein; Similar to Staphylococcus aureus autolysis regulatory protein LytS TR:Q53705 (EMBL:L42945) (584 aa) fasta scores: E(): 0, 30.5% id in 583 aa, and to Escherichia coli hypothetical protein YehU SW:YEHU_ECOLI (P33357) (561 aa) fasta scores: E(): 0, 67.8% id in 552 aa.
 
 0.976
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.724
barA
Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa.
  
 
0.687
arcB
Similar to Escherichia coli aerobic respiration control sensor protein ArcB SW:ARCB_ECOLI (P22763) (776 aa) fasta scores: E(): 0, 75.9% id in 781 aa, and to Vibrio cholerae sensor histidine kinase FexB or VC2369 TR:Q9KPJ8 (EMBL:AE004307) (785 aa) fasta scores: E(): 0, 58.8% id in 779 aa.
  
 
 0.681
yohK
Putative membrane protein; Similar to Escherichia coli hypothetical 24.5 kDa protein in pbpG-cdd intergenic region YohK SW:YOHK_ECOLI (P33373) (231 aa) fasta scores: E(): 0, 76.6% id in 231 aa,and to Vibrio cholerae hypothetical protein Vc1232 TR:Q9KSM4 (EMBL:AE004202) (224 aa) fasta scores: E(): 0,52.9% id in 225 aa.
 
  
 0.629
YPO3965
Probable hybrid two-component system regulatory protein. CDS contains both sensor histidine kinase domain and response regulator receiver domain. C-terminus is similar to Rhizobium leguminosarum regulatory protein FixL TR:Q52824 (EMBL:Z70305) (641 aa) fasta scores: E(): 0,33.3% id in 519 aa, and to Pseudomonas syringae histidine protein kinase-response regulator hybrid protein CvgsY TR:Q9WWH9 (EMBL:AF133262) (671 aa) fasta scores: E(): 0,44.6% id in 383 aa.
  
 
 0.601
YPO0256
Two-component sensor/regulator; Similar to Salmonella typhimurium pathogenicity island regulator gene SpiR TR:P74862 (EMBL:U51927) (823 aa) fasta scores: E(): 0, 46.5% id in 826 aa and to Vibrio cholerae sensory box sensor histidine kinase/response regulator VieS VC1653 TR:Q9KRI8 (EMBL:AE004243) (1146 aa) fasta scores: E(): 0, 30.4% id in 559 aa. This CDS carries both the sensor and response regulator domains.
  
 
 0.590
rcsC
Two component sensor kinase/response regulator protein RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
  
 
 0.590
tyrA
Similar to Escherichia coli T-protein [includes: chorismate mutase and prephenate dehydrogenase] TyrA SW:TYRA_ECOLI (P07023) (373 aa) fasta scores: E(): 0, 86.9% id in 373 aa, and to Erwinia herbicola T-protein [includes: chorismate mutase and prephenate dehydrogenase] TyrA SW:TYRA_ERWHE (Q02287) (373 aa) fasta scores: E(): 0, 86.0% id in 372 aa.
       0.551
YPO1181
Putative membrane protein; Similar to Escherichia coli hypothetical 8.7 kDa protein in gapA-rnd intergenic region YeaQ SW:YEAQ_ECOLI (P76246) (82 aa) fasta scores: E(): 1.8e-23, 82.9% id in 82 aa, and to Escherichia coli transglycosylase associated protein SW:TAG1_ECOLI (P76011) (84 aa) fasta scores: E(): 1.7e-16, 63.4% id in 82 aa.
   
    0.528
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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