node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO56939.1 | recA | PSPTO_3464 | PSPTO_4033 | DNA ligase, ATP-dependent, putative; Similar to GP:15158571; identified by sequence similarity; putative. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.508 |
AAO56939.1 | recG | PSPTO_3464 | PSPTO_0065 | DNA ligase, ATP-dependent, putative; Similar to GP:15158571; identified by sequence similarity; putative. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.428 |
AAO56939.1 | recO | PSPTO_3464 | PSPTO_4215 | DNA ligase, ATP-dependent, putative; Similar to GP:15158571; identified by sequence similarity; putative. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.429 |
AAO56939.1 | recX | PSPTO_3464 | PSPTO_4032 | DNA ligase, ATP-dependent, putative; Similar to GP:15158571; identified by sequence similarity; putative. | recX protein; Modulates RecA activity; Belongs to the RecX family. | 0.640 |
AAO56939.1 | ruvC | PSPTO_3464 | PSPTO_3979 | DNA ligase, ATP-dependent, putative; Similar to GP:15158571; identified by sequence similarity; putative. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.421 |
AAO57315.1 | AAO57491.1 | PSPTO_3848 | PSPTO_4034 | DNA internalization-related competence protein ComEC/Rec2; Identified by match to PFAM protein family HMM PF00753. | cinA domain protein; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR00199; Belongs to the CinA family. | 0.490 |
AAO57315.1 | radA | PSPTO_3848 | PSPTO_4640 | DNA internalization-related competence protein ComEC/Rec2; Identified by match to PFAM protein family HMM PF00753. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.522 |
AAO57315.1 | recA | PSPTO_3848 | PSPTO_4033 | DNA internalization-related competence protein ComEC/Rec2; Identified by match to PFAM protein family HMM PF00753. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.648 |
AAO57315.1 | recG | PSPTO_3848 | PSPTO_0065 | DNA internalization-related competence protein ComEC/Rec2; Identified by match to PFAM protein family HMM PF00753. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.607 |
AAO57315.1 | recX | PSPTO_3848 | PSPTO_4032 | DNA internalization-related competence protein ComEC/Rec2; Identified by match to PFAM protein family HMM PF00753. | recX protein; Modulates RecA activity; Belongs to the RecX family. | 0.675 |
AAO57315.1 | ruvA | PSPTO_3848 | PSPTO_3978 | DNA internalization-related competence protein ComEC/Rec2; Identified by match to PFAM protein family HMM PF00753. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.593 |
AAO57315.1 | ruvC | PSPTO_3848 | PSPTO_3979 | DNA internalization-related competence protein ComEC/Rec2; Identified by match to PFAM protein family HMM PF00753. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.523 |
AAO57491.1 | AAO57315.1 | PSPTO_4034 | PSPTO_3848 | cinA domain protein; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR00199; Belongs to the CinA family. | DNA internalization-related competence protein ComEC/Rec2; Identified by match to PFAM protein family HMM PF00753. | 0.490 |
AAO57491.1 | recA | PSPTO_4034 | PSPTO_4033 | cinA domain protein; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR00199; Belongs to the CinA family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.757 |
AAO57491.1 | recX | PSPTO_4034 | PSPTO_4032 | cinA domain protein; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR00199; Belongs to the CinA family. | recX protein; Modulates RecA activity; Belongs to the RecX family. | 0.651 |
radA | AAO57315.1 | PSPTO_4640 | PSPTO_3848 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | DNA internalization-related competence protein ComEC/Rec2; Identified by match to PFAM protein family HMM PF00753. | 0.522 |
radA | recA | PSPTO_4640 | PSPTO_4033 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.851 |
radA | recG | PSPTO_4640 | PSPTO_0065 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.507 |
radA | recX | PSPTO_4640 | PSPTO_4032 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | recX protein; Modulates RecA activity; Belongs to the RecX family. | 0.857 |
radA | ruvA | PSPTO_4640 | PSPTO_3978 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.439 |