node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gspA | ohrB | BSU38430 | BSU13160 | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | 0.817 |
gspA | rsbV | BSU38430 | BSU04710 | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Anti-anti-sigma factor (antagonist of RsbW); Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B. | 0.631 |
gspA | rsbW | BSU38430 | BSU04720 | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | 0.671 |
gspA | ydaE | BSU38430 | BSU04200 | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10220166; Belongs to the D-lyxose ketol-isomerase family. | 0.444 |
gspA | ydaG | BSU38430 | BSU04220 | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative general stress protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.826 |
gspA | yfkM | BSU38430 | BSU07850 | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | General stress protein 18; Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins. | 0.817 |
gspA | yflT | BSU38430 | BSU07550 | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Heat stress induced protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | 0.870 |
gspA | yhdN | BSU38430 | BSU09530 | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Aldo/keto reductase specific for NADPH; Aldo-keto reductase (AKR) that displays broad substrate specificity in vitro. Is able to reduce the standard AKR substrates DL- glyceraldehyde, D-erythrose, methylglyoxal, p-nitrobenzaldehyde, benzaldehyde and butyraldehyde, in the presence of NADPH. Cannot use NADH as a cosubstrate. Does not act on glucose, 2-pyridine carboxyaldehyde, fructose and xylose. The physiological function of this enzyme is not clear. May play a role in bacterial stress response and/or in detoxification of reactive aldehydes. Belongs to the aldo/keto reductase family. A [...] | 0.832 |
gspA | ysnF | BSU38430 | BSU28340 | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative stress response protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype. | 0.749 |
gspA | ywzA | BSU38430 | BSU38180 | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.757 |
ohrB | gspA | BSU13160 | BSU38430 | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | Putative glycosyl transferase (general stress protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.817 |
ohrB | rsbV | BSU13160 | BSU04710 | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | Anti-anti-sigma factor (antagonist of RsbW); Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B. | 0.503 |
ohrB | rsbW | BSU13160 | BSU04720 | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | 0.635 |
ohrB | ydaE | BSU13160 | BSU04200 | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10220166; Belongs to the D-lyxose ketol-isomerase family. | 0.427 |
ohrB | ydaG | BSU13160 | BSU04220 | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | Putative general stress protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.853 |
ohrB | yfkM | BSU13160 | BSU07850 | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | General stress protein 18; Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins. | 0.818 |
ohrB | yflT | BSU13160 | BSU07550 | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | Heat stress induced protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | 0.916 |
ohrB | yhdN | BSU13160 | BSU09530 | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | Aldo/keto reductase specific for NADPH; Aldo-keto reductase (AKR) that displays broad substrate specificity in vitro. Is able to reduce the standard AKR substrates DL- glyceraldehyde, D-erythrose, methylglyoxal, p-nitrobenzaldehyde, benzaldehyde and butyraldehyde, in the presence of NADPH. Cannot use NADH as a cosubstrate. Does not act on glucose, 2-pyridine carboxyaldehyde, fructose and xylose. The physiological function of this enzyme is not clear. May play a role in bacterial stress response and/or in detoxification of reactive aldehydes. Belongs to the aldo/keto reductase family. A [...] | 0.729 |
ohrB | ysnF | BSU13160 | BSU28340 | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | Putative stress response protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype. | 0.736 |
ohrB | ywzA | BSU13160 | BSU38180 | Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.796 |