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mtnA mtnA mtnP mtnP Acid_7115 Acid_7115 Acid_0320 Acid_0320 Acid_4184 Acid_4184 Acid_1334 Acid_1334 Acid_3191 Acid_3191 Acid_6718 Acid_6718 apt apt Acid_1487 Acid_1487 Acid_4056 Acid_4056
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
mtnATranslation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (343 aa)    
Predicted Functional Partners:
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
 
 
 0.971
Acid_7115
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: aba:Acid345_3426 homocysteine S-methyltransferase.
   
  
 0.874
Acid_0320
PFAM: class II aldolase/adducin family protein; KEGG: aba:Acid345_4482 class II aldolase/adducin-like.
 
  
 0.832
Acid_4184
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.827
Acid_1334
PFAM: class II aldolase/adducin family protein; KEGG: rba:RB2568 L-fuculose-phosphate aldolase.
 
  
 0.818
Acid_3191
PFAM: ribulose-phosphate 3-epimerase; KEGG: aba:Acid345_0074 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
   0.814
Acid_6718
PFAM: GHMP kinase; KEGG: dre:569254 hypothetical protein LOC569254.
 
      0.799
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
    0.792
Acid_1487
PFAM: Redoxin domain protein; KEGG: sth:STH734 cytochrome c biogenesis protein.
       0.775
Acid_4056
PFAM: class II aldolase/adducin family protein; KEGG: rba:RB681 probable L-fuculose-phosphate aldolase.
 
  
 0.768
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
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