STRINGSTRING
argR argR argH argH argF argF argJ argJ argB argB argC argC argG argG Acid_2719 Acid_2719 Acid_1357 Acid_1357 dacA dacA Acid_1567 Acid_1567
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argRTranscriptional regulator, ArgR family; Regulates arginine biosynthesis genes. (145 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase; KEGG: dsy:DSY0786 hypothetical protein; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
  
  
 0.973
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
  
 0.939
argJ
N-acetylglutamate synthase / glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
  
 0.899
argB
N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
  
 0.896
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.887
argG
PFAM: argininosuccinate synthase; KEGG: pol:Bpro_1599 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
  
  
 0.886
Acid_2719
TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: aba:Acid345_0626 acetylornithine and succinylornithine aminotransferases.
  
  
 0.777
Acid_1357
PFAM: aminotransferase class-III; KEGG: aba:Acid345_3098 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.772
dacA
Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
   
    0.744
Acid_1567
TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: aba:Acid345_2140 competence-damaged protein; Belongs to the CinA family.
 
    0.506
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
Server load: low (24%) [HD]