node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acid_0181 | Acid_1039 | Acid_0181 | Acid_1039 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | 0.999 |
Acid_0181 | Acid_1674 | Acid_0181 | Acid_1674 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | Aminotransferase; PFAM: ABC-1 domain protein; aminotransferase class-III; KEGG: nfa:nfa14400 putative aminotransferase. | 0.632 |
Acid_0181 | Acid_2458 | Acid_0181 | Acid_2458 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: aba:Acid345_4300 porphobilinogen synthase; Belongs to the ALAD family. | 0.892 |
Acid_0181 | Acid_3181 | Acid_0181 | Acid_3181 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sat:SYN_02272 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | 0.930 |
Acid_0181 | hemA | Acid_0181 | Acid_3178 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.774 |
Acid_0181 | hemC | Acid_0181 | Acid_3179 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.991 |
Acid_0181 | hemE | Acid_0181 | Acid_5202 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.918 |
Acid_0181 | hemL | Acid_0181 | Acid_4251 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: mta:Moth_1244 glutamate-1-semialdehyde-2,1-aminomutase. | 0.743 |
Acid_1039 | Acid_0181 | Acid_1039 | Acid_0181 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | 0.999 |
Acid_1039 | Acid_1674 | Acid_1039 | Acid_1674 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | Aminotransferase; PFAM: ABC-1 domain protein; aminotransferase class-III; KEGG: nfa:nfa14400 putative aminotransferase. | 0.529 |
Acid_1039 | Acid_2458 | Acid_1039 | Acid_2458 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: aba:Acid345_4300 porphobilinogen synthase; Belongs to the ALAD family. | 0.722 |
Acid_1039 | Acid_3181 | Acid_1039 | Acid_3181 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sat:SYN_02272 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | 0.999 |
Acid_1039 | hemA | Acid_1039 | Acid_3178 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.600 |
Acid_1039 | hemC | Acid_1039 | Acid_3179 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.783 |
Acid_1039 | hemL | Acid_1039 | Acid_4251 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: mta:Moth_1244 glutamate-1-semialdehyde-2,1-aminomutase. | 0.847 |
Acid_1674 | Acid_0181 | Acid_1674 | Acid_0181 | Aminotransferase; PFAM: ABC-1 domain protein; aminotransferase class-III; KEGG: nfa:nfa14400 putative aminotransferase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | 0.632 |
Acid_1674 | Acid_1039 | Acid_1674 | Acid_1039 | Aminotransferase; PFAM: ABC-1 domain protein; aminotransferase class-III; KEGG: nfa:nfa14400 putative aminotransferase. | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | 0.529 |
Acid_1674 | Acid_2458 | Acid_1674 | Acid_2458 | Aminotransferase; PFAM: ABC-1 domain protein; aminotransferase class-III; KEGG: nfa:nfa14400 putative aminotransferase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: aba:Acid345_4300 porphobilinogen synthase; Belongs to the ALAD family. | 0.947 |
Acid_1674 | Acid_3181 | Acid_1674 | Acid_3181 | Aminotransferase; PFAM: ABC-1 domain protein; aminotransferase class-III; KEGG: nfa:nfa14400 putative aminotransferase. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sat:SYN_02272 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | 0.815 |
Acid_1674 | hemA | Acid_1674 | Acid_3178 | Aminotransferase; PFAM: ABC-1 domain protein; aminotransferase class-III; KEGG: nfa:nfa14400 putative aminotransferase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.884 |