node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acid_0253 | Acid_2673 | Acid_0253 | Acid_2673 | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation. | 0.943 |
Acid_0253 | Acid_2676 | Acid_0253 | Acid_2676 | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: sso:SSO0407 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase. | 0.971 |
Acid_0253 | Acid_3250 | Acid_0253 | Acid_3250 | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tte:TTE1574 cystathionine gamma-synthase. | 0.947 |
Acid_0253 | Acid_3332 | Acid_0253 | Acid_3332 | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: sso:SSO0407 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase. | 0.938 |
Acid_0253 | Acid_4184 | Acid_0253 | Acid_4184 | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.968 |
Acid_0253 | Acid_5643 | Acid_0253 | Acid_5643 | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: aba:Acid345_1913 cystathionine gamma-synthase. | 0.954 |
Acid_0253 | Acid_7115 | Acid_0253 | Acid_7115 | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: aba:Acid345_3426 homocysteine S-methyltransferase. | 0.994 |
Acid_0253 | ahcY | Acid_0253 | Acid_5273 | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.968 |
Acid_0253 | metK | Acid_0253 | Acid_5274 | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.966 |
Acid_1262 | Acid_4184 | Acid_1262 | Acid_4184 | PFAM: purine and other phosphorylases, family 1; KEGG: mag:amb1368 nucleoside phosphorylase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.432 |
Acid_1262 | Acid_7115 | Acid_1262 | Acid_7115 | PFAM: purine and other phosphorylases, family 1; KEGG: mag:amb1368 nucleoside phosphorylase. | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: aba:Acid345_3426 homocysteine S-methyltransferase. | 0.456 |
Acid_1262 | ahcY | Acid_1262 | Acid_5273 | PFAM: purine and other phosphorylases, family 1; KEGG: mag:amb1368 nucleoside phosphorylase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.927 |
Acid_2673 | Acid_0253 | Acid_2673 | Acid_0253 | PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation. | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | 0.943 |
Acid_2673 | Acid_2676 | Acid_2673 | Acid_2676 | PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation. | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: sso:SSO0407 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase. | 0.943 |
Acid_2673 | Acid_3250 | Acid_2673 | Acid_3250 | PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tte:TTE1574 cystathionine gamma-synthase. | 0.950 |
Acid_2673 | Acid_3332 | Acid_2673 | Acid_3332 | PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation. | PFAM: Methionine synthase, vitamin-B12 independent; KEGG: sso:SSO0407 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase. | 0.943 |
Acid_2673 | Acid_4184 | Acid_2673 | Acid_4184 | PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.961 |
Acid_2673 | Acid_5643 | Acid_2673 | Acid_5643 | PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: aba:Acid345_1913 cystathionine gamma-synthase. | 0.943 |
Acid_2673 | Acid_7115 | Acid_2673 | Acid_7115 | PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation. | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: aba:Acid345_3426 homocysteine S-methyltransferase. | 0.977 |
Acid_2673 | ahcY | Acid_2673 | Acid_5273 | PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.926 |