node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACP_0864 | ACP_1241 | ACP_0864 | ACP_1241 | Beta-galactosidase; Identified by match to protein family HMM PF02449; match to protein family HMM PF08532. | Identified by match to protein family HMM PF02449; match to protein family HMM PF08532; match to protein family HMM PF08533. | 0.924 |
ACP_0864 | pepA | ACP_0864 | ACP_2959 | Beta-galactosidase; Identified by match to protein family HMM PF02449; match to protein family HMM PF08532. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.596 |
ACP_1241 | ACP_0864 | ACP_1241 | ACP_0864 | Identified by match to protein family HMM PF02449; match to protein family HMM PF08532; match to protein family HMM PF08533. | Beta-galactosidase; Identified by match to protein family HMM PF02449; match to protein family HMM PF08532. | 0.924 |
ACP_1241 | pepA | ACP_1241 | ACP_2959 | Identified by match to protein family HMM PF02449; match to protein family HMM PF08532; match to protein family HMM PF08533. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.596 |
ACP_2252 | pepA | ACP_2252 | ACP_2959 | Identified by match to protein family HMM PF01712. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.681 |
ACP_3309 | aspC | ACP_3309 | ACP_2334 | Aspartate aminotransferase; Identified by similarity to SP:P23034; match to protein family HMM PF00155; match to protein family HMM PF00266; match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM PF01276. | Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155. | 0.914 |
ACP_3309 | cysK2 | ACP_3309 | ACP_2729 | Aspartate aminotransferase; Identified by similarity to SP:P23034; match to protein family HMM PF00155; match to protein family HMM PF00266; match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM PF01276. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139. | 0.902 |
ACP_3309 | pepA | ACP_3309 | ACP_2959 | Aspartate aminotransferase; Identified by similarity to SP:P23034; match to protein family HMM PF00155; match to protein family HMM PF00266; match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM PF01276. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.812 |
aspC | ACP_3309 | ACP_2334 | ACP_3309 | Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155. | Aspartate aminotransferase; Identified by similarity to SP:P23034; match to protein family HMM PF00155; match to protein family HMM PF00266; match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM PF01276. | 0.914 |
aspC | cysK2 | ACP_2334 | ACP_2729 | Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139. | 0.902 |
aspC | pepA | ACP_2334 | ACP_2959 | Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.812 |
cysK2 | ACP_3309 | ACP_2729 | ACP_3309 | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139. | Aspartate aminotransferase; Identified by similarity to SP:P23034; match to protein family HMM PF00155; match to protein family HMM PF00266; match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM PF01276. | 0.902 |
cysK2 | aspC | ACP_2729 | ACP_2334 | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139. | Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155. | 0.902 |
cysK2 | metH | ACP_2729 | ACP_3337 | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.878 |
cysK2 | pepA | ACP_2729 | ACP_2959 | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.845 |
glyA | metH | ACP_2846 | ACP_3337 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.934 |
glyA | pepA | ACP_2846 | ACP_2959 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.838 |
icsS2 | pepA | ACP_2544 | ACP_2959 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.582 |
metH | cysK2 | ACP_3337 | ACP_2729 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139. | 0.878 |
metH | glyA | ACP_3337 | ACP_2846 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.934 |