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rpiA rpiA rpe rpe tkt tkt prs prs rpiB rpiB TDE_1640 TDE_1640 TDE_0864 TDE_0864 TDE_1998 TDE_1998 polA polA pdxS pdxS TDE_1639 TDE_1639
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (239 aa)    
Predicted Functional Partners:
rpe
Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.961
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 0.952
prs
Phosphoribosyl pyrophosphate synthetase; Identified by similarity to SP:P47304; match to protein family HMM PF00156; match to protein family HMM TIGR01251; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 
 0.939
rpiB
Ribose 5-phosphate isomerase B; Identified by similarity to SP:P37351; match to protein family HMM PF02502; match to protein family HMM TIGR00689.
     
 0.935
TDE_1640
3-dehydroquinate dehydratase, type 1, putative/shikimate 5-dehydrogenase, putative; Identified by match to protein family HMM PF01487; match to protein family HMM PF01488.
 
  
 0.916
TDE_0864
Identified by match to protein family HMM PF02878.
    
 0.915
TDE_1998
Identified by similarity to SP:P18159; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.
    
 0.915
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.865
pdxS
Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
     
  0.800
TDE_1639
Sporulation related repeat protein; Identified by match to protein family HMM PF05036.
       0.773
Your Current Organism:
Treponema denticola
NCBI taxonomy Id: 243275
Other names: T. denticola ATCC 35405, Treponema denticola ATCC 35405, Treponema denticola str. ATCC 35405
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