STRINGSTRING
serC serC serA serA serB2 serB2 MAP_4194c MAP_4194c thrC thrC cysK cysK MAP_0390c MAP_0390c MAP_0824 MAP_0824 serB serB MAP_0352c MAP_0352c glyA glyA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCSerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (374 aa)    
Predicted Functional Partners:
serA
SerA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.982
serB2
SerB2.
  
 
 0.982
MAP_4194c
Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.980
thrC
ThrC; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 0.953
cysK
CysK; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.922
MAP_0390c
Hypothetical protein.
  
 
 0.920
MAP_0824
Hypothetical protein.
     
 0.840
serB
SerB.
  
  
 0.796
MAP_0352c
Hypothetical protein.
  
 
 0.777
glyA
GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.765
Your Current Organism:
Mycobacterium avium
NCBI taxonomy Id: 262316
Other names: M. avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K10, Mycobacterium avium subsp. paratuberculosis str. K-10, Mycobacterium avium subsp. paratuberculosis strain K-10
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.