STRINGSTRING
nadK nadK tlyA tlyA recN recN nadE nadE nadD nadD MAP_1400 MAP_1400 MAP_1398 MAP_1398 MAP_1399 MAP_1399 cobB-3 cobB-3 pntAB pntAB pntAA pntAA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
nadKHypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (308 aa)    
Predicted Functional Partners:
tlyA
TlyA.
  
  
 0.984
recN
RecN; May be involved in recombinational repair of damaged DNA.
 
  
 0.968
nadE
Hypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.958
nadD
Hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.948
MAP_1400
Hypothetical protein.
     
 0.947
MAP_1398
Hypothetical protein.
 
   
 0.939
MAP_1399
Hypothetical protein.
     
 0.930
cobB-3
Hypothetical protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.917
pntAB
PntAB.
     
 0.913
pntAA
PntAA.
     
 0.911
Your Current Organism:
Mycobacterium avium
NCBI taxonomy Id: 262316
Other names: M. avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K10, Mycobacterium avium subsp. paratuberculosis str. K-10, Mycobacterium avium subsp. paratuberculosis strain K-10
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