STRINGSTRING
fadE14 fadE14 fadD33-2 fadD33-2 mbtL mbtL fadD33 fadD33 mbtK mbtK fadB fadB fadB-2 fadB-2 fixA fixA fixB fixB MAP_2395c MAP_2395c MAP_0747 MAP_0747
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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fadE14FadE14; Catalyzes the dehydrogenation at the alpha-beta position of ACP-bound acyl chains. This results in the introduction of a double bond in the lipidic chain, which is further transferred to the epsilon- amino group of lysine residue in the mycobactin core by MbtK (By similarity). (388 aa)    
Predicted Functional Partners:
fadD33-2
FadD33_2; Activates lipidic moieties required for mycobactin biosynthesis. Converts medium- to long-chain aliphatic fatty acids into acyl adenylate, which is further transferred on to the phosphopantetheine arm of the carrier protein MbtL.
 
  
 0.981
mbtL
Hypothetical protein; Acyl carrier protein involved in the formation of acyl-S-ACP intermediates within the mycobactin biosynthesis process.
    
 0.914
fadD33
FadD33_1.
 
  
 0.805
mbtK
Hypothetical protein; Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.
  
  
 0.740
fadB
FadB_1.
  
 0.738
fadB-2
FadB_2.
  
 0.738
fixA
FixA.
 
 
 0.730
fixB
FixB.
 
 
 0.728
MAP_2395c
Hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.726
MAP_0747
Hypothetical protein.
  
     0.714
Your Current Organism:
Mycobacterium avium
NCBI taxonomy Id: 262316
Other names: M. avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K-10, Mycobacterium avium subsp. paratuberculosis K10, Mycobacterium avium subsp. paratuberculosis str. K-10, Mycobacterium avium subsp. paratuberculosis strain K-10
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