node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
guaA | rplA | Exig_0439 | Exig_0084 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.976 |
guaA | rplB | Exig_0439 | Exig_0099 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.785 |
guaA | rplC | Exig_0439 | Exig_0096 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.683 |
guaA | rplJ | Exig_0439 | Exig_0085 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.974 |
guaA | rplK | Exig_0439 | Exig_0083 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.999 |
guaA | rplN | Exig_0439 | Exig_0106 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.595 |
guaA | rplP | Exig_0439 | Exig_0103 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.717 |
guaA | rpoB | Exig_0439 | Exig_0088 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.894 |
guaA | rpsL | Exig_0439 | Exig_0091 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.846 |
rplA | guaA | Exig_0084 | Exig_0439 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.976 |
rplA | rplB | Exig_0084 | Exig_0099 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.995 |
rplA | rplC | Exig_0084 | Exig_0096 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.995 |
rplA | rplF | Exig_0084 | Exig_0111 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.996 |
rplA | rplJ | Exig_0084 | Exig_0085 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.999 |
rplA | rplK | Exig_0084 | Exig_0083 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.999 |
rplA | rplN | Exig_0084 | Exig_0106 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.996 |
rplA | rplP | Exig_0084 | Exig_0103 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.995 |
rplA | rpoB | Exig_0084 | Exig_0088 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.974 |
rplA | rpsL | Exig_0084 | Exig_0091 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.994 |
rplB | guaA | Exig_0099 | Exig_0439 | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.785 |