STRINGSTRING
metE metE APE_2050.1 APE_2050.1 ahcY ahcY metC metC metB metB mat mat APE_1223.1 APE_1223.1 cysK cysK metG metG hom hom APE_0158.1 APE_0158.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
metEMethylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown (By similarity). (332 aa)    
Predicted Functional Partners:
APE_2050.1
Putative methylcobalamin:homocysteine methyltransferase; Putative methionine synthase.
 
  
 
0.987
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.982
metC
Cystathionine gamma-lyase.
  
 
 0.966
metB
Cystathionine gamma-synthase.
  
 
 0.966
mat
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
     
 0.923
APE_1223.1
Cystathionine beta-synthase; CBS.
  
 
 0.918
cysK
Cysteine synthase; Cysteine synthase that can also catalyze the synthesis of S- sulfo-L-cysteine from thiosulfate and O(3)-acetyl-L-serine, as well as the sulfhydrylation of L-serine by sulfide. Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.918
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
    
 0.906
hom
Homoserine dehydrogenase; HDH.
  
 
 0.895
APE_0158.1
Hypothetical protein.
  
 
 0.884
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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