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hemL hemL hemA hemA hemB hemB hemC hemC hemD hemD hemW hemW CA_C3355 CA_C3355 eno eno fabD fabD guaA guaA thiC thiC
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
hemLGlutamate-1-semialdehyde aminotransferase. (422 aa)    
Predicted Functional Partners:
hemA
Glutamil-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.998
hemB
Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Belongs to the ALAD family.
 
 
 0.998
hemC
Hydroxymrthylbilane syntase (porphobilinogen deaminase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.992
hemD
Uroporphyrinogen III syntase.
 
  
 0.982
hemW
Precorrin-2 dehydrogenase.
 
  
 0.907
CA_C3355
Polyketide synthase pksE (short-chain alcohol dehydrogenase,acyl-carrier-protein S-malonyltransferase,3-oxoacyl-(acyl-carrier-protein) synthase I domains).
 
  
 0.799
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.694
fabD
Malonyl CoA-acyl carrier protein transacylase.
    
 0.662
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.643
thiC
Thiamine monophosphate syntase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
 0.557
Your Current Organism:
Clostridium acetobutylicum
NCBI taxonomy Id: 272562
Other names: C. acetobutylicum ATCC 824, Clostridium acetobutylicum ATCC 824, Clostridium acetobutylicum DSM 792, Clostridium acetobutylicum str. ATCC 824, Clostridium acetobutylicum strain ATCC 824
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