node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS42693.1 | ftsI | MexAM1_META1p5089 | MexAM1_META1p5088 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | 0.865 |
ACS42693.1 | mraW | MexAM1_META1p5089 | MexAM1_META1p5090 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.914 |
ACS42693.1 | murE | MexAM1_META1p5089 | MexAM1_META1p5087 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.645 |
ACS42693.1 | murF | MexAM1_META1p5089 | MexAM1_META1p5086 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.645 |
ftsI | ACS42693.1 | MexAM1_META1p5088 | MexAM1_META1p5089 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.865 |
ftsI | mraW | MexAM1_META1p5088 | MexAM1_META1p5090 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.956 |
ftsI | murE | MexAM1_META1p5088 | MexAM1_META1p5087 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.978 |
ftsI | murF | MexAM1_META1p5088 | MexAM1_META1p5086 | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.929 |
mraW | ACS42693.1 | MexAM1_META1p5090 | MexAM1_META1p5089 | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.914 |
mraW | ftsI | MexAM1_META1p5090 | MexAM1_META1p5088 | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | 0.956 |
mraW | murE | MexAM1_META1p5090 | MexAM1_META1p5087 | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.841 |
mraW | murF | MexAM1_META1p5090 | MexAM1_META1p5086 | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.811 |
mraW | rpsB | MexAM1_META1p5090 | MexAM1_META1p2057 | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 30S ribosomal protein S2; Function of strongly homologous gene; structure; Belongs to the universal ribosomal protein uS2 family. | 0.777 |
mraW | rpsG | MexAM1_META1p5090 | MexAM1_META1p2149 | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.772 |
mraW | rpsI | MexAM1_META1p5090 | MexAM1_META1p2740 | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Ribosomal protein S9; Function of strongly homologous gene; structure; Belongs to the universal ribosomal protein uS9 family. | 0.778 |
mraW | rpsO | MexAM1_META1p5090 | MexAM1_META1p4417 | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 30S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.744 |
mraW | rpsP | MexAM1_META1p5090 | MexAM1_META1p0479 | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Ribosomal protein S16; Function of strongly homologous gene; structure; Belongs to the bacterial ribosomal protein bS16 family. | 0.758 |
mraW | truA | MexAM1_META1p5090 | MexAM1_META1p1528 | S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | tRNA pseudouridine synthase A (tRNA-uridine isomerase I) (tRNA pseudouridylate synthase I); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.772 |
murE | ACS42693.1 | MexAM1_META1p5087 | MexAM1_META1p5089 | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.645 |
murE | ftsI | MexAM1_META1p5087 | MexAM1_META1p5088 | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | Peptidoglycan glycosyltransferase (penicillin-binding protein); Function of strongly homologous gene; enzyme. | 0.978 |