STRINGSTRING
SSO6503 SSO6503 SSO0781 SSO0781 albA1 albA1 SSO0235 SSO0235 pyrF pyrF pfdB pfdB csl4 csl4 SSB SSB SSO0267 SSO0267 dnaG dnaG SSO2218 SSO2218
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSO6503Conserved hypothetical protein; Belongs to the UPF0147 family. (89 aa)    
Predicted Functional Partners:
SSO0781
Conserved hypothetical protein; Belongs to the UPF0148 family.
       0.718
albA1
DNA binding protein SSO10b; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. May be involved in DNA compaction. May bind rRNA and mRNA, playing a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.
  
     0.596
SSO0235
Conserved hypothetical protein; Similar to APE2598, AF2316, PH1458, Ta0670, MJ0619, MTH831.Some similarity with molybdenum cofactor biosynthesis MoaA homolog.
  
     0.586
pyrF
Orotidine 5'-phosphate decarboxylase (OMP decarboxylase) (OMPdcase) (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
     0.572
pfdB
Hypothetical protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
 
    0.534
csl4
Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
  
     0.526
SSB
Single-stranded DNA binding protein (SSB); Binds to ssDNA, binding approximately 5 nucleotides per monomer. Binding my be slightly cooperative. Inhibits the endonuclease activity of XPF.
 
     0.523
SSO0267
Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
  
    0.488
dnaG
Bacterial-like DNA primase (dnaG); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Can use NTPs but not dNTPs. Binds DNA. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine- rich transcripts and the exosome. Belongs to the archaeal DnaG primase family.
  
     0.475
SSO2218
Conserved hypothetical protein; Similarity with PH0709, PAB0882, MTH1862, MJ1474, AF0385.
  
     0.470
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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