node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clim_0309 | lpxA | Clim_0309 | Clim_2185 | Nucleotidyl transferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; KEGG: cph:Cpha266_0378 UDP-N-acetylglucosamine pyrophosphorylase. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.846 |
Clim_0309 | murA | Clim_0309 | Clim_0521 | Nucleotidyl transferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; KEGG: cph:Cpha266_0378 UDP-N-acetylglucosamine pyrophosphorylase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.952 |
Clim_0309 | murC | Clim_0309 | Clim_2501 | Nucleotidyl transferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; KEGG: cph:Cpha266_0378 UDP-N-acetylglucosamine pyrophosphorylase. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.731 |
Clim_0309 | murD | Clim_0309 | Clim_2504 | Nucleotidyl transferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; KEGG: cph:Cpha266_0378 UDP-N-acetylglucosamine pyrophosphorylase. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.450 |
Clim_0309 | murE | Clim_0309 | Clim_2507 | Nucleotidyl transferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; KEGG: cph:Cpha266_0378 UDP-N-acetylglucosamine pyrophosphorylase. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.900 |
Clim_0309 | murG | Clim_0309 | Clim_2502 | Nucleotidyl transferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; KEGG: cph:Cpha266_0378 UDP-N-acetylglucosamine pyrophosphorylase. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.556 |
Clim_1688 | Clim_2503 | Clim_1688 | Clim_2503 | TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_1869 UDP-N-acetylmuramate--L-alanine ligase. | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | 0.742 |
Clim_1688 | murA | Clim_1688 | Clim_0521 | TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_1869 UDP-N-acetylmuramate--L-alanine ligase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.765 |
Clim_1688 | murB | Clim_1688 | Clim_1194 | TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_1869 UDP-N-acetylmuramate--L-alanine ligase. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.528 |
Clim_1688 | murD | Clim_1688 | Clim_2504 | TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_1869 UDP-N-acetylmuramate--L-alanine ligase. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.732 |
Clim_1688 | murE | Clim_1688 | Clim_2507 | TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_1869 UDP-N-acetylmuramate--L-alanine ligase. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.548 |
Clim_1688 | murF | Clim_1688 | Clim_2506 | TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_1869 UDP-N-acetylmuramate--L-alanine ligase. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.710 |
Clim_1688 | murG | Clim_1688 | Clim_2502 | TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_1869 UDP-N-acetylmuramate--L-alanine ligase. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.865 |
Clim_2503 | Clim_1688 | Clim_2503 | Clim_1688 | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_1869 UDP-N-acetylmuramate--L-alanine ligase. | 0.742 |
Clim_2503 | murA | Clim_2503 | Clim_0521 | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.751 |
Clim_2503 | murB | Clim_2503 | Clim_1194 | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.514 |
Clim_2503 | murC | Clim_2503 | Clim_2501 | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.959 |
Clim_2503 | murD | Clim_2503 | Clim_2504 | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.963 |
Clim_2503 | murE | Clim_2503 | Clim_2507 | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.927 |
Clim_2503 | murF | Clim_2503 | Clim_2506 | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.957 |