node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABL64871.1 | ABL66253.1 | Cpha266_0820 | Cpha266_2261 | PFAM: chaperonin Cpn10; KEGG: cch:Cag_1167 chaperonin, 10 kDa. | KEGG: gvi:gll3802 DnaK like protein; Belongs to the heat shock protein 70 family. | 0.740 |
ABL64871.1 | clpP | Cpha266_0820 | Cpha266_2030 | PFAM: chaperonin Cpn10; KEGG: cch:Cag_1167 chaperonin, 10 kDa. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.528 |
ABL64871.1 | dnaJ | Cpha266_0820 | Cpha266_1872 | PFAM: chaperonin Cpn10; KEGG: cch:Cag_1167 chaperonin, 10 kDa. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.703 |
ABL64871.1 | dnaK | Cpha266_0820 | Cpha266_0864 | PFAM: chaperonin Cpn10; KEGG: cch:Cag_1167 chaperonin, 10 kDa. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.740 |
ABL64871.1 | groL | Cpha266_0820 | Cpha266_1936 | PFAM: chaperonin Cpn10; KEGG: cch:Cag_1167 chaperonin, 10 kDa. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.908 |
ABL64871.1 | grpE | Cpha266_0820 | Cpha266_1873 | PFAM: chaperonin Cpn10; KEGG: cch:Cag_1167 chaperonin, 10 kDa. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.753 |
ABL64871.1 | hslU | Cpha266_0820 | Cpha266_1545 | PFAM: chaperonin Cpn10; KEGG: cch:Cag_1167 chaperonin, 10 kDa. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.680 |
ABL64871.1 | htpG | Cpha266_0820 | Cpha266_1188 | PFAM: chaperonin Cpn10; KEGG: cch:Cag_1167 chaperonin, 10 kDa. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.702 |
ABL66051.1 | groL | Cpha266_2039 | Cpha266_1936 | PFAM: diacylglycerol kinase, catalytic region; KEGG: cte:CT1567 BmrU protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.827 |
ABL66253.1 | ABL64871.1 | Cpha266_2261 | Cpha266_0820 | KEGG: gvi:gll3802 DnaK like protein; Belongs to the heat shock protein 70 family. | PFAM: chaperonin Cpn10; KEGG: cch:Cag_1167 chaperonin, 10 kDa. | 0.740 |
ABL66253.1 | clpP | Cpha266_2261 | Cpha266_2030 | KEGG: gvi:gll3802 DnaK like protein; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.646 |
ABL66253.1 | dnaJ | Cpha266_2261 | Cpha266_1872 | KEGG: gvi:gll3802 DnaK like protein; Belongs to the heat shock protein 70 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.981 |
ABL66253.1 | groL | Cpha266_2261 | Cpha266_1936 | KEGG: gvi:gll3802 DnaK like protein; Belongs to the heat shock protein 70 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.829 |
ABL66253.1 | groS | Cpha266_2261 | Cpha266_1937 | KEGG: gvi:gll3802 DnaK like protein; Belongs to the heat shock protein 70 family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.740 |
ABL66253.1 | grpE | Cpha266_2261 | Cpha266_1873 | KEGG: gvi:gll3802 DnaK like protein; Belongs to the heat shock protein 70 family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.909 |
ABL66253.1 | hslU | Cpha266_2261 | Cpha266_1545 | KEGG: gvi:gll3802 DnaK like protein; Belongs to the heat shock protein 70 family. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.540 |
ABL66253.1 | htpG | Cpha266_2261 | Cpha266_1188 | KEGG: gvi:gll3802 DnaK like protein; Belongs to the heat shock protein 70 family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.954 |
clpP | ABL64871.1 | Cpha266_2030 | Cpha266_0820 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | PFAM: chaperonin Cpn10; KEGG: cch:Cag_1167 chaperonin, 10 kDa. | 0.528 |
clpP | ABL66253.1 | Cpha266_2030 | Cpha266_2261 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | KEGG: gvi:gll3802 DnaK like protein; Belongs to the heat shock protein 70 family. | 0.646 |
clpP | dnaJ | Cpha266_2030 | Cpha266_1872 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.629 |