node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAur_1878 | AAur_3285 | AAur_1878 | AAur_3285 | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | Identified by match to protein family HMM PF00012. | 0.935 |
AAur_1878 | clpP | AAur_1878 | AAur_2382 | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.412 |
AAur_1878 | clpP-2 | AAur_1878 | AAur_2381 | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | Putative ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.428 |
AAur_1878 | dnaK | AAur_1878 | AAur_1876 | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.994 |
AAur_1878 | dnaK-2 | AAur_1878 | AAur_3593 | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.974 |
AAur_1878 | groES | AAur_1878 | AAur_2875 | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperonin groES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.764 |
AAur_1878 | groL | AAur_1878 | AAur_1001 | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.781 |
AAur_1878 | groL-2 | AAur_1878 | AAur_2874 | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.786 |
AAur_1878 | grpE | AAur_1878 | AAur_1877 | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.993 |
AAur_1878 | hrcA | AAur_1878 | AAur_2235 | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.684 |
AAur_3285 | AAur_1878 | AAur_3285 | AAur_1878 | Identified by match to protein family HMM PF00012. | Putative DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556. | 0.935 |
AAur_3285 | clpP | AAur_3285 | AAur_2382 | Identified by match to protein family HMM PF00012. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.652 |
AAur_3285 | clpP-2 | AAur_3285 | AAur_2381 | Identified by match to protein family HMM PF00012. | Putative ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.651 |
AAur_3285 | dnaK | AAur_3285 | AAur_1876 | Identified by match to protein family HMM PF00012. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.927 |
AAur_3285 | dnaK-2 | AAur_3285 | AAur_3593 | Identified by match to protein family HMM PF00012. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.928 |
AAur_3285 | groES | AAur_3285 | AAur_2875 | Identified by match to protein family HMM PF00012. | Chaperonin groES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.818 |
AAur_3285 | groL | AAur_3285 | AAur_1001 | Identified by match to protein family HMM PF00012. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.802 |
AAur_3285 | groL-2 | AAur_3285 | AAur_2874 | Identified by match to protein family HMM PF00012. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.802 |
AAur_3285 | grpE | AAur_3285 | AAur_1877 | Identified by match to protein family HMM PF00012. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.929 |
AAur_3285 | hrcA | AAur_3285 | AAur_2235 | Identified by match to protein family HMM PF00012. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.765 |