node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arth_1256 | Arth_1257 | Arth_1256 | Arth_1257 | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase. | 0.989 |
Arth_1256 | Arth_2765 | Arth_1256 | Arth_2765 | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sco:SCO3311 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.741 |
Arth_1256 | Arth_2766 | Arth_1256 | Arth_2766 | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.915 |
Arth_1256 | Arth_2771 | Arth_1256 | Arth_2771 | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | TIGRFAM: protoporphyrinogen oxidase; PFAM: FAD dependent oxidoreductase; KEGG: lxx:Lxx01060 protoporphyrinogen oxidase. | 0.441 |
Arth_1256 | Arth_3111 | Arth_1256 | Arth_3111 | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_2221 uroporphyrin-III C-methyltransferase, C-terminal:siroheme synthase, N-terminal. | 0.978 |
Arth_1256 | hemA | Arth_1256 | Arth_2773 | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.576 |
Arth_1256 | hemC | Arth_1256 | Arth_2767 | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.978 |
Arth_1256 | hemE | Arth_1256 | Arth_2772 | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.946 |
Arth_1256 | hemH | Arth_1256 | Arth_2768 | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.502 |
Arth_1256 | hemL | Arth_1256 | Arth_2763 | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: lxx:Lxx01130 glutamate-1-semialdehyde 2,1-aminomutase. | 0.429 |
Arth_1257 | Arth_1256 | Arth_1257 | Arth_1256 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase. | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | 0.989 |
Arth_1257 | Arth_2765 | Arth_1257 | Arth_2765 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sco:SCO3311 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.883 |
Arth_1257 | Arth_2766 | Arth_1257 | Arth_2766 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.973 |
Arth_1257 | Arth_3111 | Arth_1257 | Arth_3111 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase. | TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_2221 uroporphyrin-III C-methyltransferase, C-terminal:siroheme synthase, N-terminal. | 0.962 |
Arth_1257 | hemA | Arth_1257 | Arth_2773 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.748 |
Arth_1257 | hemC | Arth_1257 | Arth_2767 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.988 |
Arth_1257 | hemE | Arth_1257 | Arth_2772 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.917 |
Arth_1257 | hemL | Arth_1257 | Arth_2763 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: lxx:Lxx01130 glutamate-1-semialdehyde 2,1-aminomutase. | 0.725 |
Arth_2765 | Arth_1256 | Arth_2765 | Arth_1256 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sco:SCO3311 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase. | 0.741 |
Arth_2765 | Arth_1257 | Arth_2765 | Arth_1257 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sco:SCO3311 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0307 uroporphyrin-III C-methyltransferase. | 0.883 |