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pyrE pyrE pyrF pyrF Jann_2963 Jann_2963 carB carB pyrB pyrB carA carA Jann_2712 Jann_2712 prs prs pyrC pyrC Jann_2606 Jann_2606 phnN phnN
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (228 aa)    
Predicted Functional Partners:
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
 
 0.997
Jann_2963
Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 0.983
carB
Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
 
 
 0.927
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.924
carA
Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family.
 
  
 0.910
Jann_2712
Dihydroorotate oxidase B, catalytic subunit / dihydrouracil dehydrogenase (NAD+) / dihydropyrimidine dehydrogenase (NADP+).
  
 
 0.880
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.867
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
  
 
 0.842
Jann_2606
Uracil-xanthine permease.
  
  
 0.828
phnN
Phosphonate metabolism 15-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
     
  0.800
Your Current Organism:
Jannaschia sp. CCS1
NCBI taxonomy Id: 290400
Other names: J. sp. CCS1
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