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trpA trpA trpB-2 trpB-2 trpB trpB trpC trpC trpF trpF Paes_1850 Paes_1850 trpD trpD Paes_0993 Paes_0993 Paes_0455 Paes_0455 trpE trpE glyA glyA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)    
Predicted Functional Partners:
trpB-2
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 0.999
trpB
Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.998
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: cte:CT1671 indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 
 0.998
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: cte:CT0718 N-(5'-phosphoribosyl)-anthranilate isomerase; Belongs to the TrpF family.
 
  
 0.986
Paes_1850
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cph:Cpha266_2037 glutamine amidotransferase of anthranilate synthase.
 
  
 0.958
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.948
Paes_0993
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.948
Paes_0455
TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: cte:CT1712 para-aminobenzoate synthetase, putative.
 
  
 0.942
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
  
 0.935
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
 
 0.929
Your Current Organism:
Prosthecochloris aestuarii
NCBI taxonomy Id: 290512
Other names: P. aestuarii DSM 271, Prosthecochloris aestuarii DSM 271, Prosthecochloris aestuarii SK 413, Prosthecochloris aestuarii SK413/DSMZ 271(t), Prosthecochloris aestuarii str. DSM 271, Prosthecochloris aestuarii strain DSM 271
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