STRINGSTRING
aroA aroA aroC aroC aroK aroK aroB aroB Paes_2164 Paes_2164 aroE aroE Paes_2274 Paes_2274 Paes_0612 Paes_0612 Paes_0264 Paes_0264 Paes_0455 Paes_0455 rpsU rpsU
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (434 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.995
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 
 0.986
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
 0.983
Paes_2164
PFAM: Prephenate dehydrogenase; KEGG: cph:Cpha266_2572 prephenate dehydrogenase.
  
 0.974
aroE
Shikimate dehydrogenase substrate binding domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 0.927
Paes_2274
PFAM: Chorismate mutase; KEGG: cch:Cag_0046 chorismate mutase, putative.
  
  
 0.807
Paes_0612
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: cph:Cpha266_0628 glutamate synthase (NADH) large subunit.
  
    0.645
Paes_0264
KEGG: plt:Plut_1983 aspartate kinase region; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding.
  
  
 0.612
Paes_0455
TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: cte:CT1712 para-aminobenzoate synthetase, putative.
 
   
 0.574
rpsU
PFAM: ribosomal protein S21; KEGG: cph:Cpha266_2278 30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
       0.541
Your Current Organism:
Prosthecochloris aestuarii
NCBI taxonomy Id: 290512
Other names: P. aestuarii DSM 271, Prosthecochloris aestuarii DSM 271, Prosthecochloris aestuarii SK 413, Prosthecochloris aestuarii SK413/DSMZ 271(t), Prosthecochloris aestuarii str. DSM 271, Prosthecochloris aestuarii strain DSM 271
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