node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A1E_02050 | A1E_03035 | A1E_02050 | A1E_03035 | COG0350 Methylated DNA-protein cysteine methyltransferase. | DNA helicase II; COG0210 Superfamily I DNA and RNA helicases. | 0.705 |
A1E_02050 | pheT | A1E_02050 | A1E_03265 | COG0350 Methylated DNA-protein cysteine methyltransferase. | phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.534 |
A1E_02050 | polA | A1E_02050 | A1E_04970 | COG0350 Methylated DNA-protein cysteine methyltransferase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.913 |
A1E_02050 | recA | A1E_02050 | A1E_04865 | COG0350 Methylated DNA-protein cysteine methyltransferase. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.780 |
A1E_02050 | ruvA | A1E_02050 | A1E_03475 | COG0350 Methylated DNA-protein cysteine methyltransferase. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.578 |
A1E_02050 | ruvB | A1E_02050 | A1E_03460 | COG0350 Methylated DNA-protein cysteine methyltransferase. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.611 |
A1E_03035 | A1E_02050 | A1E_03035 | A1E_02050 | DNA helicase II; COG0210 Superfamily I DNA and RNA helicases. | COG0350 Methylated DNA-protein cysteine methyltransferase. | 0.705 |
A1E_03035 | pheT | A1E_03035 | A1E_03265 | DNA helicase II; COG0210 Superfamily I DNA and RNA helicases. | phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.701 |
A1E_03035 | polA | A1E_03035 | A1E_04970 | DNA helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.960 |
A1E_03035 | recA | A1E_03035 | A1E_04865 | DNA helicase II; COG0210 Superfamily I DNA and RNA helicases. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.953 |
A1E_03035 | ruvA | A1E_03035 | A1E_03475 | DNA helicase II; COG0210 Superfamily I DNA and RNA helicases. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.612 |
A1E_03035 | ruvB | A1E_03035 | A1E_03460 | DNA helicase II; COG0210 Superfamily I DNA and RNA helicases. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.748 |
A1E_03035 | ruvC-2 | A1E_03035 | A1E_00600 | DNA helicase II; COG0210 Superfamily I DNA and RNA helicases. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.575 |
A1E_03035 | topA | A1E_03035 | A1E_03865 | DNA helicase II; COG0210 Superfamily I DNA and RNA helicases. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.906 |
A1E_03480 | ruvA | A1E_03480 | A1E_03475 | Hypothetical protein. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.777 |
pheT | A1E_02050 | A1E_03265 | A1E_02050 | phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | COG0350 Methylated DNA-protein cysteine methyltransferase. | 0.534 |
pheT | A1E_03035 | A1E_03265 | A1E_03035 | phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA helicase II; COG0210 Superfamily I DNA and RNA helicases. | 0.701 |
pheT | polA | A1E_03265 | A1E_04970 | phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.928 |
pheT | recA | A1E_03265 | A1E_04865 | phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.751 |
pheT | ruvA | A1E_03265 | A1E_03475 | phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.589 |