node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A1C_00475 | A1C_00480 | A1C_00475 | A1C_00480 | COG0488 ATPase components of ABC transporters with duplicated ATPase domains. | Hypothetical protein. | 0.777 |
A1C_00475 | A1C_03555 | A1C_00475 | A1C_03555 | COG0488 ATPase components of ABC transporters with duplicated ATPase domains. | KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.408 |
A1C_00475 | kdsA | A1C_00475 | A1C_00485 | COG0488 ATPase components of ABC transporters with duplicated ATPase domains. | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 0.666 |
A1C_00480 | A1C_00475 | A1C_00480 | A1C_00475 | Hypothetical protein. | COG0488 ATPase components of ABC transporters with duplicated ATPase domains. | 0.777 |
A1C_00480 | kdsA | A1C_00480 | A1C_00485 | Hypothetical protein. | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 0.668 |
A1C_00640 | A1C_03555 | A1C_00640 | A1C_03555 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.773 |
A1C_00640 | A1C_05295 | A1C_00640 | A1C_05295 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | COG0836 Mannose-1-phosphate guanylyltransferase. | 0.624 |
A1C_00640 | kdsA | A1C_00640 | A1C_00485 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 0.687 |
A1C_00640 | kdsB | A1C_00640 | A1C_02855 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.981 |
A1C_00640 | lpxC | A1C_00640 | A1C_01850 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.871 |
A1C_00640 | lpxD | A1C_00640 | A1C_00050 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.876 |
A1C_00640 | lpxK | A1C_00640 | A1C_05575 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.998 |
A1C_03555 | A1C_00475 | A1C_03555 | A1C_00475 | KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | COG0488 ATPase components of ABC transporters with duplicated ATPase domains. | 0.408 |
A1C_03555 | A1C_00640 | A1C_03555 | A1C_00640 | KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.773 |
A1C_03555 | A1C_05295 | A1C_03555 | A1C_05295 | KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | COG0836 Mannose-1-phosphate guanylyltransferase. | 0.548 |
A1C_03555 | kdsA | A1C_03555 | A1C_00485 | KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 0.994 |
A1C_03555 | kdsB | A1C_03555 | A1C_02855 | KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.943 |
A1C_03555 | lpxC | A1C_03555 | A1C_01850 | KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.677 |
A1C_03555 | lpxD | A1C_03555 | A1C_00050 | KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.683 |
A1C_03555 | lpxK | A1C_03555 | A1C_05575 | KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.843 |