STRINGSTRING
lipB lipB lipA lipA acpP acpP A1C_05945 A1C_05945 A1C_06780 A1C_06780 A1C_02720 A1C_02720 A1C_06790 A1C_06790 A1C_01890 A1C_01890 A1C_03700 A1C_03700
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
lipBLipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (209 aa)    
Predicted Functional Partners:
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.998
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.959
A1C_05945
3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
   
 0.823
A1C_06780
Hypothetical protein.
       0.818
A1C_02720
COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH).
    
  0.800
A1C_06790
Hypothetical protein; COG3023 Negative regulator of beta-lactamase expression.
       0.733
A1C_01890
Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.665
A1C_03700
Biotin--protein ligase; COG0340 Biotin-(acetyl-CoA carboxylase) ligase.
     
 0.485
Your Current Organism:
Rickettsia akari
NCBI taxonomy Id: 293614
Other names: R. akari str. Hartford, Rickettsia akari str. Hartford, Rickettsia akari strain Hartford
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