STRINGSTRING
metAA metAA BPUM_0854 BPUM_0854 BPUM_1027 BPUM_1027 BPUM_0356 BPUM_0356 BPUM_2888 BPUM_2888 BPUM_1026 BPUM_1026 hisI hisI thrB thrB metN metN BPUM_2931 BPUM_2931 BPUM_1119 BPUM_1119
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (302 aa)    
Predicted Functional Partners:
BPUM_0854
O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol.
 
 
 0.963
BPUM_1027
Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions.
  
  
 0.960
BPUM_0356
Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; Belongs to the aspartokinase family.
 
  0.896
BPUM_2888
Homoserine dehydrogenase.
  
 
 0.890
BPUM_1026
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.850
hisI
phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
 
    0.814
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
  
 0.739
metN
Methionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
  
    0.735
BPUM_2931
Methionine ABC transporter permease.
  
    0.730
BPUM_1119
Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine.
 
 
 0.716
Your Current Organism:
Bacillus pumilus
NCBI taxonomy Id: 315750
Other names: B. pumilus SAFR-032, Bacillus pumilus SAFR-032, Bacillus pumilus str. SAFR-032, Bacillus pumilus strain SAFR-032
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.