node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BPUM_0869 | BPUM_2003 | BPUM_0869 | BPUM_2003 | Histidine kinase. | Chemotaxis protein. | 0.994 |
BPUM_0869 | BPUM_2403 | BPUM_0869 | BPUM_2403 | Histidine kinase. | single-stranded-DNA-specific exonuclease RecJ. | 0.423 |
BPUM_0869 | ligA | BPUM_0869 | BPUM_0626 | Histidine kinase. | Aromatic ring-opening dioxygenase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.470 |
BPUM_0869 | polA | BPUM_0869 | BPUM_2551 | Histidine kinase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.479 |
BPUM_0869 | ruvB | BPUM_0869 | BPUM_2415 | Histidine kinase. | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.812 |
BPUM_2003 | BPUM_0869 | BPUM_2003 | BPUM_0869 | Chemotaxis protein. | Histidine kinase. | 0.994 |
BPUM_2003 | ruvB | BPUM_2003 | BPUM_2415 | Chemotaxis protein. | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.776 |
BPUM_2403 | BPUM_0869 | BPUM_2403 | BPUM_0869 | single-stranded-DNA-specific exonuclease RecJ. | Histidine kinase. | 0.423 |
BPUM_2403 | ligA | BPUM_2403 | BPUM_0626 | single-stranded-DNA-specific exonuclease RecJ. | Aromatic ring-opening dioxygenase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.648 |
BPUM_2403 | polA | BPUM_2403 | BPUM_2551 | single-stranded-DNA-specific exonuclease RecJ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.589 |
BPUM_2403 | queA | BPUM_2403 | BPUM_2413 | single-stranded-DNA-specific exonuclease RecJ. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.567 |
BPUM_2403 | ruvA | BPUM_2403 | BPUM_2416 | single-stranded-DNA-specific exonuclease RecJ. | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.571 |
BPUM_2403 | ruvB | BPUM_2403 | BPUM_2415 | single-stranded-DNA-specific exonuclease RecJ. | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.677 |
BPUM_2414 | queA | BPUM_2414 | BPUM_2413 | Hypothetical protein. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.826 |
BPUM_2414 | ruvA | BPUM_2414 | BPUM_2416 | Hypothetical protein. | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.840 |
BPUM_2414 | ruvB | BPUM_2414 | BPUM_2415 | Hypothetical protein. | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.938 |
BPUM_2414 | tgt | BPUM_2414 | BPUM_2412 | Hypothetical protein. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] | 0.681 |
ligA | BPUM_0869 | BPUM_0626 | BPUM_0869 | Aromatic ring-opening dioxygenase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Histidine kinase. | 0.470 |
ligA | BPUM_2403 | BPUM_0626 | BPUM_2403 | Aromatic ring-opening dioxygenase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | single-stranded-DNA-specific exonuclease RecJ. | 0.648 |
ligA | pheT | BPUM_0626 | BPUM_2521 | Aromatic ring-opening dioxygenase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | phenylalanyl-tRNA synthase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.529 |