STRINGSTRING
RPC_3351 RPC_3351 RPC_2450 RPC_2450 RPC_4115 RPC_4115 RPC_3511 RPC_3511 RPC_3512 RPC_3512 RPC_4343 RPC_4343 mdh1 mdh1 mdh2 mdh2 RPC_2337 RPC_2337 glcB glcB pckA pckA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPC_33512,3-dimethylmalate lyase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. (288 aa)    
Predicted Functional Partners:
RPC_2450
Citrate synthase; Belongs to the citrate synthase family.
  
 0.969
RPC_4115
L-lactate dehydrogenase (cytochrome).
   
 
 0.937
RPC_3511
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
 
 0.935
RPC_3512
2-methylcitrate dehydratase.
 
  
 0.935
RPC_4343
Pyruvate phosphate dikinase.
   
 
 0.933
mdh1
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.932
mdh2
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.932
RPC_2337
Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+)., Phosphate acetyltransferase.
    
 0.922
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.920
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.919
Your Current Organism:
Rhodopseudomonas palustris BisB18
NCBI taxonomy Id: 316056
Other names: R. palustris BisB18, Rhodopseudomonas palustris str. BisB18, Rhodopseudomonas palustris strain BisB18
Server load: low (16%) [HD]