node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACE03399.1 | ACE04990.1 | Cphamn1_0435 | Cphamn1_2081 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Glutathione synthase; PFAM: RimK domain protein ATP-grasp; KEGG: cch:Cag_0947 D-alanine-D-alanine ligase and related ATP-grasp enzyme-like. | 0.504 |
ACE03399.1 | uppP | Cphamn1_0435 | Cphamn1_1869 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.918 |
ACE04785.1 | ACE04787.1 | Cphamn1_1868 | Cphamn1_1870 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cch:Cag_0481 phosphoesterase PHP-like. | 0.451 |
ACE04785.1 | ACE04788.1 | Cphamn1_1868 | Cphamn1_1871 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: protein of unknown function DUF140; KEGG: pvi:Cvib_0490 protein of unknown function DUF140. | 0.444 |
ACE04785.1 | pdxJ | Cphamn1_1868 | Cphamn1_1867 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.488 |
ACE04785.1 | uppP | Cphamn1_1868 | Cphamn1_1869 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.838 |
ACE04787.1 | ACE04785.1 | Cphamn1_1870 | Cphamn1_1868 | PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cch:Cag_0481 phosphoesterase PHP-like. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.451 |
ACE04787.1 | ACE04788.1 | Cphamn1_1870 | Cphamn1_1871 | PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cch:Cag_0481 phosphoesterase PHP-like. | PFAM: protein of unknown function DUF140; KEGG: pvi:Cvib_0490 protein of unknown function DUF140. | 0.776 |
ACE04787.1 | uppP | Cphamn1_1870 | Cphamn1_1869 | PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cch:Cag_0481 phosphoesterase PHP-like. | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.439 |
ACE04788.1 | ACE04785.1 | Cphamn1_1871 | Cphamn1_1868 | PFAM: protein of unknown function DUF140; KEGG: pvi:Cvib_0490 protein of unknown function DUF140. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.444 |
ACE04788.1 | ACE04787.1 | Cphamn1_1871 | Cphamn1_1870 | PFAM: protein of unknown function DUF140; KEGG: pvi:Cvib_0490 protein of unknown function DUF140. | PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cch:Cag_0481 phosphoesterase PHP-like. | 0.776 |
ACE04788.1 | pdxJ | Cphamn1_1871 | Cphamn1_1867 | PFAM: protein of unknown function DUF140; KEGG: pvi:Cvib_0490 protein of unknown function DUF140. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.418 |
ACE04788.1 | uppP | Cphamn1_1871 | Cphamn1_1869 | PFAM: protein of unknown function DUF140; KEGG: pvi:Cvib_0490 protein of unknown function DUF140. | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.453 |
ACE04990.1 | ACE03399.1 | Cphamn1_2081 | Cphamn1_0435 | Glutathione synthase; PFAM: RimK domain protein ATP-grasp; KEGG: cch:Cag_0947 D-alanine-D-alanine ligase and related ATP-grasp enzyme-like. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.504 |
ACE04990.1 | mraY | Cphamn1_2081 | Cphamn1_2525 | Glutathione synthase; PFAM: RimK domain protein ATP-grasp; KEGG: cch:Cag_0947 D-alanine-D-alanine ligase and related ATP-grasp enzyme-like. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.753 |
ACE04990.1 | uppP | Cphamn1_2081 | Cphamn1_1869 | Glutathione synthase; PFAM: RimK domain protein ATP-grasp; KEGG: cch:Cag_0947 D-alanine-D-alanine ligase and related ATP-grasp enzyme-like. | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.442 |
mraY | ACE04990.1 | Cphamn1_2525 | Cphamn1_2081 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Glutathione synthase; PFAM: RimK domain protein ATP-grasp; KEGG: cch:Cag_0947 D-alanine-D-alanine ligase and related ATP-grasp enzyme-like. | 0.753 |
mraY | uppP | Cphamn1_2525 | Cphamn1_1869 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.910 |
pdxJ | ACE04785.1 | Cphamn1_1867 | Cphamn1_1868 | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.488 |
pdxJ | ACE04788.1 | Cphamn1_1867 | Cphamn1_1871 | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | PFAM: protein of unknown function DUF140; KEGG: pvi:Cvib_0490 protein of unknown function DUF140. | 0.418 |