node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ppro_2440 | Ppro_2441 | Ppro_2440 | Ppro_2441 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain; KEGG: tbd:Tbd_0099 NAD-dependent epimerase/dehydratase. | PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: gsu:GSU1942 UDP-glucose/GDP-mannose dehydrogenase family protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.979 |
Ppro_2440 | Ppro_2450 | Ppro_2440 | Ppro_2450 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain; KEGG: tbd:Tbd_0099 NAD-dependent epimerase/dehydratase. | PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mxa:MXAN_1101 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.927 |
Ppro_2440 | glmU | Ppro_2440 | Ppro_0501 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain; KEGG: tbd:Tbd_0099 NAD-dependent epimerase/dehydratase. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.909 |
Ppro_2440 | lpxA | Ppro_2440 | Ppro_3021 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain; KEGG: tbd:Tbd_0099 NAD-dependent epimerase/dehydratase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.816 |
Ppro_2440 | murA | Ppro_2440 | Ppro_3044 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain; KEGG: tbd:Tbd_0099 NAD-dependent epimerase/dehydratase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.904 |
Ppro_2441 | Ppro_2440 | Ppro_2441 | Ppro_2440 | PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: gsu:GSU1942 UDP-glucose/GDP-mannose dehydrogenase family protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain; KEGG: tbd:Tbd_0099 NAD-dependent epimerase/dehydratase. | 0.979 |
Ppro_2441 | Ppro_2450 | Ppro_2441 | Ppro_2450 | PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: gsu:GSU1942 UDP-glucose/GDP-mannose dehydrogenase family protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mxa:MXAN_1101 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.989 |
Ppro_2441 | glmU | Ppro_2441 | Ppro_0501 | PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: gsu:GSU1942 UDP-glucose/GDP-mannose dehydrogenase family protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.925 |
Ppro_2441 | lpxA | Ppro_2441 | Ppro_3021 | PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: gsu:GSU1942 UDP-glucose/GDP-mannose dehydrogenase family protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.822 |
Ppro_2441 | murA | Ppro_2441 | Ppro_3044 | PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: gsu:GSU1942 UDP-glucose/GDP-mannose dehydrogenase family protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.904 |
Ppro_2450 | Ppro_2440 | Ppro_2450 | Ppro_2440 | PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mxa:MXAN_1101 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain; KEGG: tbd:Tbd_0099 NAD-dependent epimerase/dehydratase. | 0.927 |
Ppro_2450 | Ppro_2441 | Ppro_2450 | Ppro_2441 | PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mxa:MXAN_1101 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: gsu:GSU1942 UDP-glucose/GDP-mannose dehydrogenase family protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.989 |
Ppro_2450 | glmS | Ppro_2450 | Ppro_0093 | PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mxa:MXAN_1101 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.466 |
Ppro_2450 | glmU | Ppro_2450 | Ppro_0501 | PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mxa:MXAN_1101 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.934 |
Ppro_2450 | lpxA | Ppro_2450 | Ppro_3021 | PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mxa:MXAN_1101 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.827 |
Ppro_2450 | murA | Ppro_2450 | Ppro_3044 | PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mxa:MXAN_1101 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.919 |
glmM | glmS | Ppro_2256 | Ppro_0093 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.937 |
glmM | glmU | Ppro_2256 | Ppro_0501 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.951 |
glmM | murA | Ppro_2256 | Ppro_3044 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.496 |
glmM | murC | Ppro_2256 | Ppro_3288 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.525 |